91042 - Molecular Pharmacology and Pharmacotherapy of Biotechnological Drugs

Academic Year 2025/2026

  • Moduli: Gloria Ravegnini (Modulo 1)
  • Teaching Mode: Traditional lectures (Modulo 1)
  • Campus: Rimini
  • Corso: Single cycle degree programme (LMCU) in Pharmacy (cod. 5987)

    Also valid for Single cycle degree programme (LMCU) in Pharmacy (cod. 9078)

Learning outcomes

At the end of the module the student: - knows the structure, production and post-translational processes of recombinant proteins, purification processes and therapeutic targets of biotechnological drugs on the market; - knows the different classes of therapeutic proteins and monoclonal antibodies and their pharmacodynamic and pharmacokinetic profile; - knows the profile of activity, immunogenicity and safety of biotechnological drugs and biosimilars; - knows how to apply the knowledge learned for the conduct of the profession, for the proper conservation and dispensation of biotechnological drugs and to inform and educate patients in their use and monitor the management of appropriateness in their use and the continuity of adherence to drug therapy in chronic therapies.

Course contents

GENETIC ENGINEERING AND RECOMBINANT DNA

MONOCLONAL ANTIBODIES

Oligonucleotides as Drugs Classification of oligonucleotides. Mechanism of action of oligonucleotides.

PHARMACODYNAMICS

PHARMACOKINETICS

CLINICAL USE OF BIOTECHNOLOGICAL DRUGS DRUGS FOR THE CARDIOVASCULAR SYSTEM

DRUGS FOR THE CENTRAL NERVOUS SYSTEM DRUGS FOR THE RESPIRATORY SYSTEM

Safety of biosimilar drugs.

ADVANCED THERAPY: Cells as drugs

GENE THERAPY TARGET THERAPY TARGETED DRUGS IN ONCOLOGY

EPIGENETIC DRUGS CLINICAL USE OF BIOTECHNOLOGICAL DRUGS

DRUGS FOR ONCOLOGY

DRUGS FOR THE IMMUNE SYSTEM

ADVERSE EFFECTS of Biotechnological Drugs

Teaching methods

Il corso è organizzato in lezioni frontali

Assessment methods

- In order to take the examination, the student must have attended at least 70% of the lectures. Students are reminded to check the prerequisites listed in the course structure diagram.

-  Students with learning disorders and\or temporary or permanent disabilities: please, contact the office responsible (https://site.unibo.it/studenti-con-disabilita-e-dsa/en/for-students) as soon as possible so that they can propose acceptable adjustments. The request for adaptation must be submitted in advance (15 days before the exam date) to the lecturer, who will assess the appropriateness of the adjustments, taking into account the teaching objectives.

Assessment of learning consists in an oral exam, for each module, which aims to verify and evaluate the achievement of the learning objectives.
The student evaluations takes into account the correctness of the answers, the understanding of the principles learned showed by the student. In addition, the level of exposure, also in relation to the previous knowledge necessary for the understanding of the specific exam subject will be considered. The duration of the oral exam is on average 20-30 minutes.

Office hours

See the website of Gloria Ravegnini