PhD in Cardio Nephro Thoracic Sciences

Academic Year 2020-2021
Subject area Medical, Pharmaceutical and Veterinary Medical Sciences
Cycle 36
Coordinator Prof. Gaetano Domenico Gargiulo
Language English, Italian
Duration 3 years
Positions 7 positions. More information in the PhD Programme Table.
Application deadline May 21, 2020 at 01:00 PM (Expired)
Enrolment period From Jul 21, 2020 to Jul 30, 2020
Doctoral programme start date Nov 01, 2020
Operating centre
Bologna
Main Department
Department of Medical and Surgical Sciences - DIMEC
Associated Departments
Department of Experimental, Diagnostic and Specialty Medicine - DIMES
Research topics

Curriculum 1: Cardiology/Cardiac Surgery

  • Pulmonary Hypertension: Pharmacotherapy of induction
  • New perspectives in the treatment of acute and chronic ischemic heart disease
  • New approaches to percutaneous treatment of aortic and mitral valve disease
  • Personalized therapy, "genetic driven", of cardiomyopathies
  • New techniques of catheter ablation for the treatment of arrhythmias
  • Brain protection in aortic arch surgery
  • Myocardial protection in cardiac surgery
  • Heart transplantation. Aortic valve replacement with prosthesis sutereless
  • Frozen elephant trunk technique surgery for extensive diseases of the thoracic aorta
  • Decellularized scaffolds in paediatric cardiac surgery.

 

Curriculum 2: Nephrology/Urology

  • Imaging in the diagnosis, staging and restaging of prostate cancer, evaluation of the role of new radiotracers for PET in identifying the presence of lymph node metastases using the histological gold standard diagnostic.
  • Assessing the role of PET in restaging of patients with recurrent disease and the main clinical indicators maybe related to a positive imaging.
  • Evaluation of the multiparametric MR in the local staging of disease prior to surgery and in patients in active surveillance for prostate cancer indolent.
  • Laparoscopy in urology oncology.
  • Application of laser technology for the treatment of benign prostatic hypertrophy (HoLEP).
  • Retrograde treatment of kidney stones through the use of flexible instruments (RIRS, retrograde intrarenalsurgery) and the technique combined antegrade-retrograde (ECIRS (endoscopiccombinedintrarenalsurgery).

 

Curriculum 3: Pulmonary Diseases/Thoracic Surgery

  • Technological innovations in the treatment of acute and chronic respiratory failure.
  • Physiopathological mechanisms of exacerbation of chronic respiratory disorders.
  • Home monitoring for chronic respiratory patients.
  • Prevention of the respiratory infections in critically ill patients.
  • Surgical therapy of experimental model of pulmonary hypertension.
  • Pathogenetic factors of fibrosis in the esophageal gastro-esophageal reflux disease.
  • Biomolecular characteristics of pathogenesis of esophageal adenocarcinoma.
  • The neuroendocrine tumors of the chest: from neuroepithelial bodies & Co. to disease.
  • The role of the genetic and biomolecular markers for a multidisciplinary tailored therapy.
  • The minimally-invasive diagnostic and therapeutic approach to lung cancer: between present time and future perspectives.
  • Study of pulmonary regeneration after pneumonectomy: experimental models and their applications.
  • Enhancing lung transplantation: ex-vivo lung perfusion an other techniques.
Job opportunities and potential areas of employment
- Researcher
- Researcher in clinical SSD
- OU Medical Director in the university clinic
- Medical Director UO hospital
- Research laboratories or public or private institutions
- Research Assistant in public institutions or private.
Admission Board

Surname Name University Role Curriculum email
Daddi Niccolò Università di Bologna Member Pulmonary Diseases/Thoracic Surgery niccolo.daddi@unibo.it
La Manna Gaetano Università di Bologna Member Nephrology/Urology gaetano.lamanna@unibo.it
Pacini Davide Università di Bologna Member Cardiology/Cardiac Surgery davide.pacini@unibo.it
Bonora Elena Università di Bologna Substitute Nephrology/Urology elena.bonora6@unibo.it
Fiorentino Michelangelo Università di Bologna Substitute Nephrology/Urology michelangelo.fiorentino@unibo.it
Galiè Nazzareno Università di Bologna Substitute Cardiology/Cardiac Surgery nazzareno.galie@unibo.it
Learning outcomes
The PhD program is dedicated to Cardiology / Cardiac Surgery, Nephrology / Urology, Pulmonology /Thoracic surgery / Esophageal surgery. It is articulated in basic and clinical research in the fields of stem cells, genetics, thoracic oncology, immunology, in any area of possible development of research pertinent to the curricula in which the course of doctorate is organized.
The educational objectives are:
- the introduction to the methodology of scientific research;
- the acquisition of bibliographic research methodologies, implementation of the data base, statistical processing data;
- the acquisition of special laboratory techniques in the context of defined research projects;
- the acquisition of modern computer aids for research and communication;
- the knowledge of the basic rules a) of medical ethics in clinical research and b) the ethics of laboratory experimentation;
- the knowledge of methods of structure of research protocols.
Activities to be carried out by Doctoral candidates
Students will play the research activity understood as "learning laboratory." Common to all the addresses are the bibliographical research, understanding and review of the literature, preparation of study protocols, statistical analysis of the data collected for preparation of abstracts, communications, articles, preferably to be submitted to Congress and international journals whose access is through "peer review". Students will be primarily responsible for the "peer review" process, the presentation and discussion of the data at conferences. Students who have chosen to address the basic research, will conduct laboratory activities; the others will conduct laboratory and clinical activities or clinical only. The experimental samples will be in the various options experiments and patients.
Research training activities compliant with the Doctoral programme's learning outcomes
The training consists of research laboratory and / or clinical research, coordinated by the PhD Supervisor, and educational activities, including four areas of training: Common University, common doctorates medical area, common and specific PhD.
- The University organizes the basic training on the management of research, knowledge of research systems and financing systems, exploiting the results of research and intellectual property, business culture. PhD students with specific interests can also follow advanced courses on these topics.
- The Doctoral medical area organizes courses of scientific English (24 hours, in collaboration with the University Language Centre) and safety courses in biomedical environment (12 hours, in collaboration with the Area People and Organisation of the University and with Referrals to the Security Departments of reference).
- The PhD organizes seminars held by members of the Academic Board. The main topics are those described in reference to the three curricula which make up the PhD programme.
- The Supervisor directs the PhD student to specific training events (conferences, workshops, internships, revisions of case studies, etc.) and is responsible for advanced computer training according to the research project.
Internationalization features
The PhD programme has established a cooperative relationship with universities and scientific training centers and multinational companies with intensive research and development in the biomedical field, in Europe and North America. Curriculum: Cardiology / Cardiac Surgery - University Hospital St. Luc Universitè Catholique de Louvain Brüssel Belgium; Utrecht University Hospital Heart Lung Institute Utrecht Netherlands.
Curriculum: Nefrology-Urology - Nephrology Service, Hospital Universitari Bellvitge, Universität de Barcelona; Fresenius Medical Care International - Bad Homburg Germany; Novartis.
Curriculum: Pneumology-Thoracic surgery - University of Toronto, Division of Thoracic Surgery Toronto General Hospital, Canada; Columbia University Medical Centre, NY; Presbyterian Hospital, NY, USA; Silicon Biosystems, University Hospital Zurich, Dept. of Thoracic surgery, Switzerland; Vienna Medical University, Dept. of Thoracic surgery, Austria; Universitair Ziekenhuis Leuven, Dept of Thoracic Surgery, Belgium; King’s College London, UK; Tuffs University, Boston, MA, USA; University Ghent, Gent, Belgium; European Health Center, Otwock, ECZ-Otwock, Poland.
Expected research results and products
Products and expected results of the research activities of graduate students (preferably on the basis of quantitative criteria and / or time, such as books, publications in editorial series and magazines, patents, software, postgraduate papers in national and international conferences, etc.
Doctoral programme Academic Board
Surname Name University/Institution Qualification
Bonora Elena Università di Bologna Professore Associato
Brunocilla Eugenio Università di Bologna Professore Ordinario
D'Errico Antonietta Università di Bologna Professore Ordinario
D'Ovidio Franco Columbia University - Presbyterian Hospital (NY, USA) Professore Associato
Daddi Niccolò Università di Bologna Professore Associato
El Khoury Gebrine University Catholique de Louvain Brussels (Belgium) Professore Ordinario
Fiorentino Michelangelo Università di Bologna Professore Associato
Galie' Nazzareno Università di Bologna Professore Ordinario
Gargiulo Gaetano Domenico Università di Bologna Professore Ordinario
Gnudi Luigi King’s College London (Great Britain) Professore Ordinario
Hill Nicholas S. Tufts University (Boston, USA) Professore Ordinario
La Manna Gaetano Università di Bologna Professore Associato Confermato
Marulli Giuseppe Università degli Studi di Padova Professore Associato
Minervini Andrea Università degli Studi di Firenze Professore Associato
Mottrie Alex University Ghent (Belgium) Professore Ordinario
Nardo Bruno Università di Bologna Professore Associato Confermato
Nava Stefano Università di Bologna Professore Ordinario
Pacini Davide Università di Bologna Professore Ordinario
Rosso Lorenzo Università degli Studi di Milano Professore Associato
Spaggiari Lorenzo Università degli Studi di Milano Professore Associato
Torbicki Adam Medical Centre for Postgraduate Education (Poland) Professore Ordinario
Ventura Carlo Università di Bologna Professore Ordinario
Zagari Rocco Maurizio Università di Bologna Professore Associato Confermato