17952 - Checks and Validation of Phytoderivatives

Course Unit Page


This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Good health and well-being Life on land

Academic Year 2021/2022

Learning outcomes

Aim of the course is the knowledge of the composition of microbial ecosystems and the acquisition of traditional and molecular approaches for the microbiological analysis of phytoderivatives. The experimental methods will be acquired through lab exercises.

Course contents

Taxonomy and phylogeny of microorganisms.

Analysis of microbial communities by culture-dependent methods.

Analysis of microbial communities by culture-independent molecular methods.

Microbial communities of terrestrial environments.

Microbial interactions and human microbial ecosystems.

Microbial growth and metabolism.

Microbial contamination and biohazard.

Sterilization: principles and methods.

Microbiological requirements for pharmaceutical preparations.

Sterility control.

Microbiological tests of non-sterile products.

Preservatives and validation: Challenge test.

Determination of bacterial endotoxins: LAL test.



Slides and notes taken during the lessons are essential for exam preparation. As a reference, the student can deepen the topics on the following texts:

Microbiologia Sistematica, Ambientale ed Industriale. Willey, Sherwood, Woolverton. McGraw-Hill.

Biology of Microorganisms. Brock. Global Edition.

Farmacopea Europea.

Microbiologia Industriale. Matilde Manzoni. Casa Editrice Ambrosiana.

LABORATORY NOTES with the operational description of the experiences.

Teaching methods

Lectures with the support of explanatory slides.
Laboratory exercises.

As concerns the teaching methods of this course unit, all students must attend Module 1, 2 [https://www.unibo.it/en/services-and-opportunities/health-and-assistance/health-and-safety/online-course-on-health-and-safety-in-study-and-internship-areas] online, while Module 3 on health and safety is to be attended in class. Information about Module 3 attendance schedule is available on the website of your degree programme.

Assessment methods

Oral exam in correspondence with the appeals fixed in the examination windows.

Teaching tools

PC, projector, laboratory experiences.

Office hours

See the website of Silvia Turroni