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69887 - Endocrinology

Academic Year 2020/2021

                
                        Docente:
                        Flaminia Fanelli
                    
                        Credits:
                        3
                    
                        SSD:
                        MED/13
                    
                        Language:
                        English
                    
                        Teaching Mode:
                        Traditional lectures
                        
                            Campus:
                            Bologna
                        
                            Corso:
                            Second cycle degree programme (LM) in
                            Medical Biotechnology (cod. 9081)

                            Teaching resources on Virtuale

Learning outcomes

Describe the molecular basis of endocrine systems and the pathogenesis of endocrine diseases. Discuss the development and application of novel technological strategies for the diagnosis and therapy of endocrinological disesases in the daily clinical practice. Critically read and interpret scientific literature in the field of endocrinology and metabolism.

Course contents

1) The endocrine system: function, classification. 2) The endocrine axes and the target organs 3) Food intake control. The homeostatic and hedonic control of food intake. The adipose tissue organ. Monogenic obesity. Endocrine causes of obesity. Metabolic syndrome. Obesity in rodents and its lab evaluation. 4) The basis of glicidic metabolism. Hyperinsulinism and its consequences. Type 1 and 2 diabetes mellitus. Type 2 diabetes therapy. GLP-1 derived drugs. 5) Molecular basis of thyroid carcinomas
6) Molecular basis of adrenal adenomas 7) Molecular basis of MEN-1 and MEN-2 syndromes, pituitary adenomas, parathyroid tumors 8) Molecular basis of the somatostatin use in the treatment of the neuroendocrine tumors 9) Analytical methodology for hormone measurements

Readings/Bibliography

Only as a further confirmation or as a general overview we suggest the following book:

"Core curriculum Endocrinologia e Metabolismo" di Faglia G, Beck-Peccoz P, Spada A, Lania A. Editore: Mc Graw-Hill 2009 1° edizione.

Teaching methods

The lectures will be interactive.

Two lectures will have a more technical approach to the following topics: handling of the lab animals and techniques to measure hormones

Assessment methods

The assessment is in oral form in front of a commission composed by Prof. Stanghellini and Prof. Mariani for the Internal Medicine Course and by Dr. Fanelli for the Endocrinology course.

The final note derives from the median of the three single notes obtained by the three Professors.

Teaching tools

The slides of the lectures represent the main tool. Each set of slides will be given at the end of each lecture.

At the last lecture a series of 16 pdf will be provided containing update review articles concerning the topics presented during the course.

Office hours

See the website of Flaminia Fanelli