55393 - Organic Chemistry

Course Unit Page

Academic Year 2020/2021

Learning outcomes

At the end of the class the student has a basic knowledge of the different types of organic compounds and the mechanism of the most important reactions. Also, he has a good knowledge of the structure and reactivity of the main families of bio-molecules.

Course contents

 

Chemical bond, resonance and carbon hybridization states;

Structure and reactivity of alkanes and cycloalcalnes;

Stereoisomery of the organic compounds;

The idea of reaction mechanism and alkyl halides;

Alcools and ether: nomenclature, properties, synthesis and reactivity;

Alkanes and cycloalkanes. Halogenation of alkanes. Alkene and alkyne. Addition to the CC double bond. Conjugate unsaturated systems;

Alkenes and alkynes: nomenclature, properties, synthesis and reactivity;

Benzene and the concept or aromaticity;

Aldehydes, ketones and carboxylic compounds: nomenclature, properties, synthesis and reactivity;

Amines: nomenclature, properties, synthesis and reactivity;

Carboxylic acids and analogoues: nomenclature, properties, synthesis and reactivity;

Carbohydrates: monosaccharides (structure, stereochemistry, Fischer projections), emiacetal structures, furanosides and pyranosides (Haworth projections and chair conformations, mutarotation), glycosides, examples of disaccharides, oligosaccharides and polysaccharides.

Aminoacids and proteins: a-aminoacids (structure, acidic and basic properties, stereochemistry, Fischer projections, essential a-aminoacids, proteinogenic and not), peptides (nature and geometry of the peptide bond, peptide structure), proteins (primary structure and its determination, secondary structure, tertiary and quaternary, main biological functions of proteins).

Lipids: main characteristics and classes of lipids, triglycerides (structure, synthesis and hydrolysis, properties, soaps and micelles), phospholipids (structure and functions), steroids (structure, cholesterol and lipoproteins, examples of steroidic hormones, bile acids), liposoluble vitamins (structures and functions)

Readings/Bibliography

- K.P.C. Vollhardt, N.E. Schore, "Chimica Organica", IV Ed. Zanichelli, Bologna.

- J. McMurry "Chimica Organica, un approccio biologico", Ed. Zanichelli, Bologna.

Teaching methods

The course is organized in two teaching modules held by Prof. Bandini and Prof. Calvaresi, respectively.

Both the teaching units consist of lectures followed by in-class practices on the applications of the main concepts. Lessons of the first teaching unit are focused on these topics: nomenclature and reactivity of the most common functional groups in organic chemistry as well as stereochemistry concepts.

Lessons of the second teaching unit, characterized by a descriptive approach, present the most common classes of bio-organic molecules (structure and properties)

 

Theoretical lectures. Problem solution.

Assessment methods

The goal of the oral examination can be summarized as follows:
(i) the student must possess a good knowledge of the main concepts which are essential to understand nomenclature, structure, stereochemistry and reactivity of organic molecules.
(ii) the student must be able to use the above concepts to solve simple problems of reactivity and structure in organic chemistry..

A written examination including 9 (nine) open questions will ba arranged as an assessment method (1.5 h time).

Teaching tools

Problem solution

Office hours

See the website of Marco Bandini

See the website of Matteo Calvaresi