Chemical and genomics based strategies in the discovery of novel drug targets

Year 2024
Code 8631
Campus Bologna
Credits 3
Cost 100,00 €
Starting date Jul 01, 2024
Finishing date Jul 05, 2024
Application deadline Jun 24, 2024
Course overview
The programme lasts for 5 days, classroom training is delivered in English, awards 3 CFU credits and aims the following learning outcomes iIn the last decade we have witnessed changes in the design and conduction of research in the biomedical field, resulting from the decoding of the human genome. In particular , it is relevant that the revolution has been focused on the discovery of new drugs and new drug targets thanks to genomics, transcriptomics and proteomics. The selection and validation of new drug targets requires a number of research strategies that have been developed recently. The aim of the School is to spread among young people in education and among those who are already working in this field, how to best use the tools offered by the most advanced research and updated . Experts, leaders in their field, were invited as lecturers. They will explain, through lectures and a lab exercise, the following topics: chemogenomics, drug discovery, genomics; the role of high-throughput assays; the small interfering RNA; reporter gene models in vitro and in vivo; transcription factors as new therapeutic targets; chemiluminescence Integrated systems for analysis. Finally, we will sketch the lines of the future development of these technologies. In order to better facilitate the dialogue between teachers and students, there are two moments in the middle and at the end of the course, in which students will be encouraged to ask teachers questions on the topics that most interested them. Another highlight will be the individual experience in the laboratory, where each student will engage in experiments planned under the guidance of specialized tutors.
Subject area
Sciences and technology
Number of participants
min 8 max 50
Duration
5 days
Language
English
Admission qualifications
- first cycle degree and/or second / single cycle degree obtained under D.M. 270/04 or first cycle degree and/or second / single cycle degree obtained under the laws previously in force (DM 509/99 and Old Pag. 3 a 5 Regulations) in the following fields or classes: L-2 Biotechnologies, Genomics, L-13 Biology, L-29 Pharmacy,LM-6 Biology, LM-8 Industrial Biotechnologies, LM-9 Pharmaceutical, Veterinary and Medical biotechnologies, LM-13 Pharmacy and industrial pharmacy, LM-41 Medicine, LM-54 Chemistry;

- first cycle degree and/or second / single cycle degree obtained abroad deemed equivalent to those described in point above by the admission committee, for the purposes of admission to the Summer School;

- Students enrolled in the 4th years of LM13.
Linguistic skills
attestation or self-certification of knowledge of the English language level A2
Academic director
Prof. Gabriele Campana
Study plan

-Intellectual property and biotechnological innovation
-Biased agonism at GPCRs as a novel avenue for more effective and safer drugs: the paradigm ofopioid receptors
-Integrin-based drug discovery
-Bioinformatics
-HIV Therapeutic Strategies
-NMR- computer- and enthalpy-based design of novel potent covalent XIAP inhibitors
-Genetic and epigenetic pathways in drug discovery: Nuclear receptors as pharmacologicaltarget
-Biomarkers for Alzheimer’s disease and their use in supporting drug discovery and clinical trials
-Neurobiological mechanisms in alcoholism: Translational studies in humans and rodents
-Probing Allosteric Communication with Combined Molecular Dynamics Simulations and NetworkAnalysis

Gabriele Campana

Telephone
tel. +39 051 2091852

Contacts

Gabriele Campana

Telephone
tel. +39 051 2091852