- Docente: Emil Malucelli
- Credits: 3
- SSD: BIOS-09/A
- Language: Italian
- Teaching Mode: In-person learning (entirely or partially)
- Campus: Bologna
- Corso: First cycle degree programme (L) in Biomedical Laboratory techniques (cod. 8484)
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from Sep 24, 2026 to Nov 24, 2026
Learning outcomes
The student will achivea a detailed knowledge of the regulation of the biochemical processes in different tissues (liver, muscle, brain) together with ageneraloverview ofthe main biochemical deficitsgenerating metabolic diseasesin different tissues.
Course contents
Sistematic Biochemistry
Liver. Functions and metabolic flexibility. Bile acids. Glucidic metabolism. Lipid metabolism. Protein metabolism. Detossification of xenobiotics. Protection from Oxidative damage. Ethanol metabolism.
Muscle. Contractile and regulatory proteins. Muscle contraction. Ionic channel. Calcium fluxes. Skeletal and cardiac muscle metabolism. Bioenergetics: system of energy buffers "phosphocreatine shuttle" model.
Advanced noninvasive diagnostic techniques.
Physical principles of nuclear magnetic resonace spectroscopy (NMR). NMR application in in vivo biochemistry. Integration between holistic and reductionist approaches. In vivo 31P spectroscopy in brain and skeletal muscle (31P MRS).
Readings/Bibliography
Biochimica Sistematica Umana
C.M. Caldarera
CLUEB
Fondamenti di Biochimica
D. Voet
J. Voet
C. W. Pratt
ZANICHELLI
Teaching methods
Frontal lessons
Assessment methods
Written test with 31 multiple choice questions.
Students with Specific Learning Disorders (SLD) or temporary or permanent disabilities are encouraged to contact the University's relevant support office as early as possible (https://site.unibo.it/studenti-con-disabilita-e-dsa/it ). The office will propose any appropriate accommodations for eligible students. Such accommodations must be submitted to the course instructor for approval at least 15 days in advance. The instructor will assess their suitability, taking into account the learning objectives of the course.
With regard to assessment, the use of artificial intelligence (AI) is prohibited. Any use constitutes a violation of academic integrity.
Teaching tools
Teaching material such as slides, animations, films used during lessons will be made available to studens on line. The printable material should be taken by the student to class.
Office hours
See the website of Emil Malucelli