- Docente: Vincenzo Tumiatti
- Credits: 3
- SSD: CHIM/08
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Rimini
- Corso: Long cycle 2nd degree programme in Pharmacy (cod. 0040)
Learning outcomes
The aim of the course is to explain and clarify, from the medicinal chemistry point of view, the different steps of the drug development: starting from the choice of the biological targets to the discovery of a lead compound and its optimization.
Course contents
Introduction, topics and aims of the course. Research and development of new drugs. Biological targets selection. The starting point: lead compound. Lead modification and strategies related to, molecular modelling. Patents: advantages, structure, examples. Research metodologies by internet data banks, the use of the most common free chemistry softwares.
Readings/Bibliography
F. Gualtieri, M.N. Romanelli, E. Teodori Chimica Farmaceutica dei recettori, CLUEB, Bologna, 1997.
L.P. Graham. An introduction to Medicinal Chemistry, Oxford University Press, 2005.
Further material will be supplied during the Course
Teaching methods
During the lessons will be treated the different parts of the program.
Assessment methods
In order to pass this exam it will be required orally the knowledge of the subjects reported in the program.
Teaching tools
All the teaching program wiil be explained by PC power point presentation and, when necessary, by using the molecular models.
Office hours
See the website of Vincenzo Tumiatti