CompBioMed2

A Centre of Excellence in Computational Biomedicine

Abstract

CompBioMed2 is a proposal for the second phase of the Computational Biomedicine Centre of Excellence (CoE), CompBioMed, an outward facing CoE comprising members from academia, industry and the healthcare sector. CompBioMed has established itself as a hub for practitioners in the field, successfully nucleating a substantial body of research, education, training, innovation and outreach within the nascent field of Computational Biomedicine. Computational Biomedicine is an emergent technology that will enable clinicians to develop and refine personalised medicine strategies ahead of their clinical delivery to the patient. Medical regulatory authorities are currently embracing the prospect of using in silico methods in the area of clinical trials and we intend to be in the vanguard of this activity, laying the groundwork for the application of HPC-based Computational Biomedicine approaches to a greater number of therapeutic areas. The HPC requirements of our users are as diverse as the communities we represent. We support both monolithic codes, potentially scaling to the exascale, and complex workflows requiring support for advanced execution patterns. Understanding the complex outputs of such simulations requires both rigorous uncertainty quantification and the embrace of the convergence of HPC and high performance data analytics (HPDA). CompBioMed2 seeks to combine these approaches with the large, heterogeneous datasets from medical records and from the experimental laboratory to underpin clinical decision support systems. CompBioMed2 will continue to support, nurture and grow our community of practitioners, delivering incubator activities to prepare our most mature applications for wider usage, providing avenues that will sustain CompBioMed2 wellbeyond the proposed funding period.

Project details

Unibo Team Leader: Marco Viceconti

Unibo involved Department/s:
Dipartimento di Ingegneria Industriale

Coordinator:
Ucl University College London(United Kingdom)

Other Participants:
Surfsara Bv (Netherlands)
Universitat Pompeu Fabra (Spain)
Acellera Labs Sl (Spain)
Janssen Pharmaceutica Nv (Belgium)
Barcelona Supercomputing Center - Centro Nacional De Supercomputacion (Spain)
Bayerische Akademie Der Wissenschaften (Germany)
Universite' De Geneve (Switzerland)
Cbk Sci Con Limited (United Kingdom)
ALMA MATER STUDIORUM - Università di Bologna (Italy)
Universiteit Van Amsterdam (Netherlands)
University Of Oxford (United Kingdom)
University Of Edinburgh (United Kingdom)
Evotec (Uk) Limited (United Kingdom)
Bull Sas (France)
The University Of Sheffield Usfd (United Kingdom)

Total Eu Contribution: Euro (EUR) 7.999.822,50
Project Duration in months: 48
Start Date: 01/10/2019
End Date: 30/09/2023

Cordis webpage
Project website

Good health and well-being This project contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

UE flag This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 823712