Foto del docente

Pier Luigi Martelli

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Director of Second Cycle Degree in Bioinformatics

Publications

Walsh I.; Fishman D.; Garcia-Gasulla D.; Titma T.; Pollastri G.; Capriotti E.; Casadio R.; Capella-Gutierrez S.; Cirillo D.; Del Conte A.; Dimopoulos A.C.; Del Angel V.D.; Dopazo J.; Fariselli P.; Fernandez J.M.; Huber F.; Kreshuk A.; Lenaerts T.; Martelli P.L.; Navarro A.; Broin P.O.; Pinero J.; Piovesan D.; Reczko M.; Ronzano F.; Satagopam V.; Savojardo C.; Spiwok V.; Tangaro M.A.; Tartari G.; Salgado D.; Valencia A.; Zambelli F.; Harrow J.; Psomopoulos F.E.; Tosatto S.C.E., DOME: recommendations for supervised machine learning validation in biology, «NATURE METHODS», 2021, 18, pp. 1122-1127 - 1127 [Scientific article]

Babbi G.; Savojardo C.; Martelli P.L.; Casadio R., Huntingtin: A protein with a peculiar solvent accessible surface, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, pp. 1 - 12 [Scientific article]

Savojardo C.; Babbi G.; Martelli P.L.; Casadio R., Mapping OMIM Disease–Related Variations on Protein Domains Reveals an Association Among Variation Type, Pfam Models, and Disease Classes, «FRONTIERS IN MOLECULAR BIOSCIENCES», 2021, 8, pp. 1 - 9 [Scientific article]

Savojardo C.; Martelli P.L.; Casadio R.; Fariselli P., On the critical review of five machine learning-based algorithms for predicting protein stability changes upon mutation, «BRIEFINGS IN BIOINFORMATICS», 2021, 22, pp. 601 - 603 [Scientific article]

Savojardo, Castrense; Manfredi, Matteo; Martelli, Pier Luigi; Casadio, Rita, Solvent Accessibility of Residues Undergoing Pathogenic Variations in Humans: From Protein Structures to Protein Sequences, «FRONTIERS IN MOLECULAR BIOSCIENCES», 2021, 7, pp. 1 - 9 [Scientific article]

Turri, Valentina; Latinovic, Olga S.; Bonafè, Massimiliano; Toyang, Ngeh; Parigi, Maria; Calassanzio, Matteo; Martelli, Pier Luigi; Vagheggini, Alessandro; Abbati, Giulia; Sarnelli, Anna; Casadio, Rita; Ratti, Claudio; Massi, Paola; Schoelz, James E.; Salvato, Maria S.; Piccinini, Filippo; Martinelli, Giovanni, Cauliflower Mosaic Virus TAV, a Plant Virus Protein That Functions like Ribonuclease H1 and is Cytotoxic to Glioma Cells, «BIOMED RESEARCH INTERNATIONAL», 2020, 2020, pp. 1 - 10 [Scientific article]Open Access

Savojardo C.; Bruciaferri N.; Tartari G.; Martelli P.L.; Casadio R., DeepMito: accurate prediction of protein sub-mitochondrial localization using convolutional neural networks, «BIOINFORMATICS», 2020, 36, pp. 56 - 64 [Scientific article]

Babbi G.; Baldazzi D.; Savojardo C.; Martelli P.L.; Casadio R., Highlighting human enzymes active in different metabolic pathways and diseases: The case study of EC 1.2.3.1 and EC 2.3.1.9, «BIOMEDICINES», 2020, 8, pp. 250 - 262 [Scientific article]

Savojardo C.; Martelli P.L.; Tartari G.; Casadio R., Large-scale prediction and analysis of protein sub-mitochondrial localization with DeepMito, «BMC BIOINFORMATICS», 2020, 21, pp. 266 - 278 [Scientific article]Open Access

Samuele Bovo, Pier Luigi Martelli, Pietro Di Lena, Rita Casadio, NETGE-PLUS, 2020. [Software]

Bovo S.; Martelli P.L.; Di Lena P.; Casadio R., NETGE-PLUS: Standard and Network-Based Gene Enrichment Analysis in Human and Model Organisms, «JOURNAL OF PROTEOME RESEARCH», 2020, 19, pp. 2873 - 2878 [Scientific article]

Montanucci, Ludovica; Martelli, Pier Luigi; Ben-Tal, Nir; Fariselli, Piero, A natural upper bound to the accuracy of predicting protein stability changes upon mutations, «BIOINFORMATICS», 2019, 35, pp. 1513 - 1517 [Scientific article]

Savojardo, Castrense; Babbi, Giulia; Bovo, Samuele; Capriotti, Emidio; Martelli, Pier Luigi; Casadio, Rita, Are machine learning based methods suited to address complex biological problems? Lessons from CAGI-5 challenges, «HUMAN MUTATION», 2019, 40, pp. 1455 - 1462 [Scientific article]

Kasak L.; Bakolitsa C.; Hu Z.; Yu C.; Rine J.; Dimster-Denk D.F.; Pandey G.; De Baets G.; Bromberg Y.; Cao C.; Capriotti E.; Casadio R.; Van Durme J.; Giollo M.; Karchin R.; Katsonis P.; Leonardi E.; Lichtarge O.; Martelli P.L.; Masica D.; Mooney S.D.; Olatubosun A.; Radivojac P.; Rousseau F.; Pal L.R.; Savojardo C.; Schymkowitz J.; Thusberg J.; Tosatto S.C.E.; Vihinen M.; Valiaho J.; Repo S.; Moult J.; Brenner S.E.; Friedberg I., Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants, «HUMAN MUTATION», 2019, 40, pp. 1530 - 1545 [Scientific article]

Mount S.M.; Avsec Z.; Carmel L.; Casadio R.; Celik M.H.; Chen K.; Cheng J.; Cohen N.E.; Fairbrother W.G.; Fenesh T.; Gagneur J.; Gotea V.; Holzer T.; Lin C.-F.; Martelli P.L.; Naito T.; Nguyen T.Y.D.; Savojardo C.; Unger R.; Wang R.; Yang Y.; Zhao H., Assessing predictions of the impact of variants on splicing in CAGI5, «HUMAN MUTATION», 2019, 40, pp. 1215 - 1224 [Scientific article]

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