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Pier Luigi Martelli

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Director of Second Cycle Degree in Bioinformatics

Curriculum vitae

PLM obtained his Degree with Laude in Physics at the Bologna University in 1997, discussing a thesis on "The predicion of foldons in proteins". He obtained the PhD in Physics in 2001 at the same University, discussing a thesis on "Hybrid systems of hidden Markov models and Neural Networks for the prediction of protein structure". He received different fellowships from the CNR (target project on "Molecular Genetics) and from the Consortium INBB. He had a contract researcher position at the Biocomputing Group of the University of Bologna granted by the FIRB2001 project on "Bioinformatics for genomics and proteomics". He then won a "Young researcher" position granted by the FIRB2003 project on "LIBI: International Laboratory of Bioinformatics". Since October 2001 he is enrolled at the Faculty of Mathematical, Physical and Natural Sciences of the University of Bologna as a Researcher in the Biochemistry class (BIO/10). On February 2015 he is appointed as Associatr Professor. PLM lectured at the Universities of Ferrara and Trento. He is now teaching at the International Bologna Master Course in  Bioinformatics. His research activity focuses on the development of systems based on Neural Networks, Hidden Markov Models and Support Vector Machines for the prediction of functional and structural features in proteins. In particular he developed systems for the prediction of the secondary structure of proteins, of the topology and topography of membrane proteins (both from inner and outer membranes), of the bonding state of cysteines, of the subcellular localization. Moreover he studied and simulated the protein folding process, he modelled the structure of different proteins,  integrating computational and experimental information, he analysed the interaction between proteins and ligands by means of docking procedures and molecular dynamics simulations. PLM authored more than 110 peer reviewed papers published in international journals and presented his results to more than 100 national and international meetings. He obtained the best paper award at the ISMB 2002 meeting (Edmonton, Canada).

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