28960 - Laboratory of Sustainable Methodologies in Organic Chemistry L

Academic Year 2010/2011

  • Docente: Salvatore Pollicino
  • Credits: 3
  • SSD: CHIM/06
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Rimini
  • Corso: First cycle degree programme (L) in Chemistry and Technologies for the Environment and Materials (cod. 0883)

Course contents

The program of the course starts from the knowledge acquired in the course of  Laboratory of Organic Chemistry. It is formed by two parts. The first one concerns basic informations and principles of spectroscopy  (NMR, IR, UV/VIS) and mass spectrometry (GC-MS) applied to the investigations of properties and structure of pre synthesized materials. Several dedicated instruments are available to direct use of students.

The second part of course concerns the practical preparations of  six products, in parallel to subjects discussed in the course of Organic Chemistry.

The proposed experience are as follows:

1 - Williamson synthesis of 2-ethoxynaphthalene.

2 - A greener approach to Aspirin synthesis using microwawe irradiation.

3 - Wagner-Meerwein rearrangement in homochiral molecule.  

4 - synthesis of  2-methilbenzimidazole (mesomerism and tautomerism).

5 - organometallic reactions in aqueous media: Indium-promoted addition to benzaldehyde.

6 - aldolic condensation involving kinetic and thermodinamic enolates.

Readings/Bibliography

M. D'Ischia, La Chimica Organica in Laboratorio, Casa Editrice Piccin.

G.F. Pedulli, Metodi Fisici in Chimica Organica, Casa Editrice Piccin.

Teaching methods

Detailed synthesis procedures will be furnished to each student, together with mechanicistic explanation of the considered reactions and NMR spectra of starting materials and final products. In the laboratory there are working places with suitable equipments to perform the considered reactions.

Assessment methods

Students are request to have an oral examination at the same time of the examination of course Organic Chemistry. Subjects of the examination will be the reaction mechanisms of tha studied reations and the characterization of the obtained products.

Students are request to write detailed reports on all programmed experiences.

Teaching tools

Copies of all slides reported in class room will be fournished.

Office hours

See the website of Salvatore Pollicino