37200 - Chemistry andBiochemistry I (LZ-C)

Academic Year 2021/2022

  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 8415)

Course contents

Structure and properties of carbohydrates and lipids

Carbohydrates. Monosaccharides: aldoses and ketoses, in linear and cyclic forms. Anomers. Glycosidic bonds. Disaccharides and polysaccharides (starch, glycogen, cellulose, glycosaminoglycans). Glycoconiugates.

Lipids. Triacylglycerols and other acylglycerols, glycerophospholipids, sphingophospholipids, glycosphingolipids, cholesterol and cholesterol esters. Isoprenoids. Lipids and biological membranes.

 

Cofactors and coenzymes

General properties and main coenzymes that serve as carries of electrons and functional groups.

 

Thermodynamic aspects of biochemical processes and cellular bioenergetics

Laws of thermodynamics and biological systems; Gibbs free energy and chemical potential; relationship between equilibrium constants and standard free-energy changes of chemical reactions. Thermodynamics and transmembrane transport systems.

Coupled reactions and high energy compounds; phosphoryl group transfer potential; ATP role; ortho- and pyrophosphoric cleavage and mode of usage of ATP for energy transfer; redox reactions and free-energy changes.

Office hours

See the website of Flavio Flamigni