- Docente: Giovanni Perini
- Credits: 6
- SSD: BIO/18
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Second cycle degree programme (LM) in Molecular and cellular biology (cod. 8021)
Learning outcomes
Students will acquire notions about the basic molecular mechanisms
responsible for epigenetic phenomena with a special emphasis
on X-chromosome inactivation, allelic exclusion and DNA methylation
dynamics during embryogenesis
Course contents
Lectures will deal with the following subject matters: X-chromosome
inactivation, Genomic imprinting, Allelic exclusion, paramutation
in plants, RNA interference, chromatin organization, DNA
methylation dynamics during embryogenesis, HSP90 buffering.
Readings/Bibliography
Scientific papers from top ranked journals such as Cell, Science, and Nature.
Teaching methods
Standard lectures and paper-reading
Assessment methods
Written exam consisting in eight open questions and one problem, followed by an oral exam.
Teaching tools
Slides and papers from scientific journals
Office hours
See the website of Giovanni Perini