90967 - Organic Chemistry

Course Unit Page

Academic Year 2022/2023

Learning outcomes

The course involves the study of the structure, properties, reactions, and preparation of organic compounds, which are sorted into organic families defined by their functional groups. At the end of the course, the student will understand the fundamental principles of organic chemistry, the main synthetic methods to obtain organic compounds, and the structure-reactivity relationship governing the behavior of organic molecules, with broader reference to medicinal chemistry and life science.

Course contents

Part 1 (Prof.ssa Claudia Tomasini)

Structure and Bonding

Acids and Bases

Introduction to Organic Molecules and Functional Groups

Alkanes and Cycloalkanes


Understanding Organic Reactions

Alkyl Halides -Nucleophilic Substitution and Elimination Reactions

Alkenes - electrophilic addition



Part 2 (Prof. Luca Valgimigli)

Alcohols, Ethers, and Epoxides

Oxidation and Reduction

Radical Reactions

Conjugation, Resonance

Benzene and Aromatic Compounds - electrophilic aromatic substitution

Carboxylic Acids and the Acidity of the O–H Bond

Introduction to Carbonyl Chemistry; Organometallic Reagents

Aldehydes and Ketones—Nucleophilic Addition

Carboxylic Acids and Their Derivatives—Nucleophilic Acyl Substitution


Part 3 (Dott.ssa Demetra Giuri)

Substitution Reactions of Carbonyl Compounds at the α Carbon

Carbonyl Condensation Reactions


Amines, Amino Acids and Proteins



Organic Chemistry 6th Edition By Janice Smith

ISBN10: 1260119106
ISBN13: 9781260119107

McGraw Hill

Teaching methods

The topics listed in the program will be fully covered, with a particular attention to the reaction mechanisms.

Assessment methods

The preparation is tested by a written exam, whose aim is to verify both the knowledge of the subject.

Teaching tools

Overhead projector, PC, blackboard

Office hours

See the website of Claudia Tomasini

See the website of Luca Valgimigli

See the website of Demetra Giuri