70385 - Genomics-Based Strategies in the Discovery of Novel Drug Targets

Course Unit Page

  • Teacher Santi Mario Spampinato

  • Credits 3

  • SSD BIO/14

  • Teaching Mode Traditional lectures

  • Language English

  • Campus of Bologna

  • Degree Programme Second cycle degree programme (LM) in Pharmaceutical Biotechnology (cod. 9068)

SDGs

This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Good health and well-being Quality education Industry, innovation and infrastructure

Academic Year 2021/2022

Learning outcomes

The course is focused on the international summer school Chemical and Genomics Strategies in the Discovery of Novel Drug Targets. The main aim of the course is to expose young students to international experts' new ideas in the develpoment of drugs. It offers a unique opportunity to participants to discuss with experts on the latest research results.

Course contents

The summer school that corresponds to this course.  generally is held at the end of June, 2022. The topica are: gunctional genomics screening strategy to identify novel mitochondrial regulators; intellectual property and biotechnological innovation; in-vivo gene network modelling and control in microfluidics; Strategies against SARS-CoV-2:drugs, vaccines and monoclonal antibodies; anti-integrin therapy: new molecular insights and potential clinical applications of integrin ligands; biomarkers for Alzheimer’s disease and their use in supporting drug discovery and clinical trials; biased agonism, low intrinsic efficacy or combination treatments? molecular pathway analysis to identify the most promising avenue for more effective and safer analgesics; targeting pharmacologically viable protein-protein interactions via combinatorial library screening (HTS by NMR) and Lys covalent agents; computational annotation of "Omics" data; PROteolysis TArgeting Chimeras (PROTACs): new horizons in the development of drugs and therapeutic modalities; genetic and epigenetic pathways in drug discovery: Nuclear receptors as pharmacological targets.

Assessment methods

Lessons and a lab course

Office hours

See the website of Santi Mario Spampinato