37200 - Chemistry andBiochemistry I (LZ-B)

Course Unit Page

Academic Year 2021/2022

Course contents

Cofactors and coenzymes

 General properties and main coenzymes that serve as carries of electrons and functional groups.

 

Structure and properties of carbohydrates and lipids

Carbohydrates. Monosaccharides: aldoses and ketoses, in linear and cyclic forms. Anomers. Glycosidic bonds. Disaccharides and polysaccharides (starch, glycogen, cellulose, glycosaminoglycans). Glycoconiugates.

Lipids, neutral and polar: triacylglycerols and other acylglycerols, glycerophospholipids, sphingophospholipids, glycosphingolipids, cholesterol and cholesterol esters. Lipids and biological membranes. Isoprenoids.

 

Principles of cellular bioenergetics

Chemical potential; Delta G and Delta G’°; relationship between equilibrium constants and standard free-energy changes of chemical reactions. Thermodynamics and transmembrane transport systems.

Coupled reactions and high energy compounds; phosphoryl group transfer potential; ATP role; ortho- and pyrophosphoric cleavage and mode of usage of ATP for energy transfer; redox reactions and free-energy changes.

Office hours

See the website of Giulio Agnetti