06944 - Complements of Organic Chemistry

Learning outcomes

At the end of the course the student completes his knowledge of basic organic chemistry. We will cover topics such as organic chemistry of radicals and the chemistry of sugars. In addition to the more purely synthetic part, the main part of the course will provide a more exhaustive discussion of the most common spectroscopic techniques for the structural analysis of organic compounds. In particular, Nuclear Magnetic Resonance (NMR) and mass spectrometry (MS) will be presented as a powerful tool for the analysis of organic pollutants.

Course contents

The course will focus on the application of the principal techniques used for the structural identification and analysis of organic molecules The course will apply basic knowledge on spectroscopic methods such as Nuclear Magnetic resonance and Mass Spectroscopy to the solution of the structures of organic molecules.. The main part of the course will be carried out with exercitations on experimental data,

1. NMR Spectroscopy
   1. Nuclear spin and resonance
   2. NMR spectromers and FT technique.
   3. Spin relaxation theory
   4. Acquisition parameters, spectral width and RF pulses
   5. 1H spectra: chimica shift, cpupling constants and integration
   6. 13C spectra and DEPT techniques for the signal assignment
   7. NOE spectra
   8. exercitations
      
      
2. Mass Spectroscopy
   1. Ionization techniques: electron impact, electron spray, MALDI
      
   2. Practical exercitations on experimental mass spectra

Carbohydrates and reactivity

Radicals and reactivity

Exercises of organic synthesis with in-depth analysis of stereochemistry.

Readings/Bibliography

Testi/Bibliografia

Robert. M. Silverstein et al

IDENTIFICAZIONE SPETTROMETRICA DI COMPOSTI ORGANICI

Terza Edizione

Casa Editrice Ambrosiana

ISBN 978-88-08-18350-7

Teaching methods

Lessons supported by PowerPoint presentations and exercises. The teacher is willing to receive students outside the lesson time for additional explanations and/or discussion.

Assessment methods

The final examination will determine the level reached by the student in the objectives set out in the " Learning outcomes”

The assessment of the learning consists in a 2 hours written test, without the support of books or notes but with the periodic table.

To carry out the written exam registration is required through "Alma exams ", in respect of the mandatory deadlines.

The written test include 3 questions giving a value of 12 points each. The exercises consist in the synthesis of complex organic molecules.

The maximum score is therefore 36 out of 30, the honor (cum laude) is automatic after reaching 32 points.

Teaching tools

Presentations in PDF file by the teacher, protected under password, are available on-line in the web-site iol.unibo.it

Office hours

See the website of Mauro Comes Franchini