39196 - Methodologies for Clinical Research (BO)

Course Unit Page

  • Teacher Adriana Semprini

  • Credits 2

  • Teaching Mode Traditional lectures

  • Language Italian

  • Campus of Bologna

  • Degree Programme First cycle degree programme (L) in Physiotherapy (cod. 8476)

  • Course Timetable from Mar 01, 2022 to Jun 23, 2022


This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.

Good health and well-being Quality education Partnerships for the goals

Academic Year 2021/2022

Learning outcomes

After completing this module the student will have knowledge of the aims and methods of evidence-based practice, he will have the ability to apply knowledge and understanding in relation to the formulation of clinical questions, conducting literature searches and developing research protocols in physiotherapy.

Course contents

1. Evidence Based Practice (EBP) in Physiotherapy

1.0. Qualitative and Quantitave Research

1.1. The New Evidence Pyramid

1.2. The Evidence Based Practice process

1.2.1. The search question (PICOM)

1.2.2. The scanning and searching in the databases of:


systematic reviews


point of care

1.2.3. The Critical Appraisal of evidence:

truth Value

clinical Relevance



The Risk Of Bias Tools (Jadad-PEDroScore-CochraneROB2, ROBINS, QUIPS, QUADS2, CASP, AMSTAR2-ROBIS, AGREE2)

1.2.4. The patient empowerment

2. Research Methodology

2.1. The Randomized Controlled Trials with conducting&reporting tools (CONSORT checklist)

The observational studies with conducting&reporting tools (STROBE checklist)

The case series and case reports  with conducting&reporting tools (CARE checklist)

The diagnostic studies with conducting&reporting tools (STARD checklist)

2.2. The scoping reviews with conducting&reporting tools (PRISMA ScR checklist)

The systematic reviews and meta-analisis with conducting&reporting tools (PRISMA 2020 checklist)

2.3. The Guidelines with conducting&reporting tools (AGREE reporting checklist)

3. The Ethics Committee and patient involvement in research

The World Medical Association Declaration of Helsinki


1. Valerio Barbari, Niccolò Ramponi

Evidence Based Practice. La guida completa per il professionista della salute.

Fisioscience ed., Verona 2021

2. Paolo Chiari, Daniela Mosci, Enrico Naldi, Centro Studi EBN

Evidence-BasedClinicalPracticeLa pratica clinico-assistenzialebasata su prove di efficacia. 2/ed

The McGraw-Hill Companies Publishing Group Italia, Milano 2011

3. Elizabeth Domholdt

Rehabilitation Research: Principles And Applications.

Elsevier Saunders, 2005

Teaching methods

Frontal lessons and practices or PBL exercises individual or in team.

Assessment methods

Written and oral, as follow:

- The written part involves the elaboration of a thesis which initially consists of a brief review of the literature according to the indications of the PRISMA ScR checklist with respect to the section of the methods and flow-chart of the studies included in the results. In a second moment, choice of only 1 study, among those included, of which to make an in-depth critical appraisal. Once the essay has been sent (at least one week before the exam), if deemed sufficient, the oral exam will take place with presentation of the article included in the review and 3 questions on the general theory of lesson topics.

- The oral exam will allow you to raise or lower the score of the written exam by a maximum of 3 points.

The use of mobile phones or supporting material such as handouts or notes is not allowed during the test.

Teaching tools

PC (with connection to internet and to biomedical databases and AlmaRE digital collections) and video-projector.

Office hours

See the website of Adriana Semprini