- Docente: Damiano Genovese
- Credits: 4
- SSD: CHIM/03
- Language: English
- Teaching Mode: Traditional lectures
- Campus: Rimini
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Corso:
Single cycle degree programme (LMCU) in
Pharmacy (cod. 5987)
Also valid for Single cycle degree programme (LMCU) in Pharmacy (cod. 9078)
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from Feb 29, 2024 to May 23, 2024
Learning outcomes
The Nanoscience for Pharmacy and Medicine course aims to provide the student with the fundamentals of the chemical (a.k.a. "bottom-up") approach to the application of nanotechnology in the pharmaceutical and biomedical fields. Through a description of (i) the chemical basis of processes at the nanoscale, (ii) the characterization techniques of nanomaterials, and (iii) the design strategies of nanomaterials themselves, the student acquires the tools to gain an overview of the potential of nanoscience for modern medicine, in diagnostic and therapeutic areas.
Course contents
Nanosciences for Pharmacy and Medicine:
1) Introduction to nanomedicine
- Multimodal Nanomaterials
- Theranostic Nanomaterials
- Active and Passive Targeting
2) Lifecycle of a Nanomaterial
- Colloidal Stability of Nanomaterials
- Dynamic Light Scattering and Zeta Potential
- Mechanisms for Cell Internalizatio
- Intracellular drug release
- Excretion routes of nanomaterials
3) Silica Nanoparticles
- Synthetic Methods
- Active Targeting of silica nanoparticles
- Advanced silica nanoparticles: ultrasmall and breakable
4) Gold Nanoparticles
- Structures and properties
- Application in Diagnostic Assays
- Virustatic and Virucidal effects
5) Exosome-based Nanomaterials
- Bottom-up, top-down and hybrid methods
- Exosome doping
- Surface Functionalization
6) Other Nanomaterials
- Magnetic Nanoparticles
- RNA interference delivery nanoparticles
- Conductive nanomaterials and tissue regeneration
- Injectable nanocomposite hydrogels
Readings/Bibliography
The teaching material used for classes is available at IOL (insegnamenti on line) page.
Additional teaching material such as scientific articles, topical reviews etc will be provided during the classes, with the aim to integrate the class presentations.
Teaching methods
Classroom Lectures
Assessment methods
Oral exam.
It is possible to start the exam with presentation of a scientific paper concerning one of the topics of the course (selected by the candidate).
The remaining of the discussion will be aimed to evaluate the preparation of the student on the main topics of the course, for an overall duration of ca. 20-30 minutes.
Teaching tools
Power point presentations used during the lessons and any research material will be provided to the students in electronic format via Internet.
Office hours
See the website of Damiano Genovese