93917 - Biomedical Instrumentation

Academic Year 2021/2022

  • Docente: Elisa Magosso
  • Credits: 9
  • SSD: ING-INF/06
  • Language: English
  • Moduli: Elisa Magosso (Modulo 1) Elisa Magosso (Modulo 2)
  • Teaching Mode: Traditional lectures (Modulo 1) Traditional lectures (Modulo 2)
  • Campus: Cesena
  • Corso: Second cycle degree programme (LM) in Biomedical Engineering (cod. 9266)

Learning outcomes

The course aims at providing the operational and design principles of the most commonly used diagnostic instrumentation (instrumentation for recording bioelectrical potentials, for the acquisition of bio-images, for the measurement of forces and pressures, body flows and volumes, blood oxygenation). At the end of the class, the student knows – for each described device/instrumentation - the underlying physical phenomena, architecture, employed materials, operational modes, aspects of interaction with the human body. The student is also able to analyze and solve problems related to design of biomedical measurement instruments.

Course contents

Electronic circuits, amplifiers and filters for biomedical signals

Operational amplifier

Negative feedback amplifiers

Instrumentation amplifier

Active filters

Other analogic feedback circuits (adder circuit, differentiator/integrator, peak/amplitude detector circuits)

Measurement of electroencephalographic potentials

Electrodes for EEG

International standard for electrode positioning

Digital electroencephalographic system

Piezoelectric materials

Properties of piezoelectric materials: direct and inverse piezoelectric effect

Signal processing circuits for piezoelectric sensors (voltage amplifier, charge amplifier)


Instrumentation for Ultrasound Imaging

Basic physics of ultrasounds

Main elements of an ultrasound transducer and image generation

Electronic steering and focusing in array transducers

Measurement of flow and volume

Blood ultrasound flowmeters (phase shift, continuous-wave and pulsed-wave doppler flowmeters)

Electrical-impedance plethysmography


Monophasic trapezoidal

Biphasic trapezoidal

Laboratory activities

Characterization of an operational amplifier

Realization of a peak/amplitude detector with operational amplifier

Design and realization of a second-order filter

Square-wave generator with operational amplifier

Realization of a charge amplifier for piezoelectric pressure sensor


G. Avanzolini and E. Magosso, Strumentazione biomedica: progetto e impiego dei sistemi di misura, Pàtron Editore, Bologna, 2015, terza edizione

J.G. Webster, Medical Instrumentation: application and design, Wiley and Sons, NY, 2009, 4th edition.

J.J. Carr, J.M. Brown, Introduction to Biomedical Equipment Technology, Wiley &Sons, NY, 4th Edition, 2000.

R.S. Khandpur, Biomedical Instrumentation: Technology and Applications, McGraw-Hill Professional, 2004

V.L. Da Silveira Nantes Button, Principles of Measurement and Transduction of Biomedical Variables, Academic Press, Elsevier, 2015

Teaching methods

The course consists of in-class lectures and laboratory activities. The letures aim at furnishing the theoretical knowledge on operational principles and design elements of the presented biomedical instrumentation. The theoretical concepts will be accompanied by exempla and exercises on analysis and design of biomedical systems. Laboratory activities using will be performed at the Biomedical Engineering Laboratory and at the Electronic and Telecommunication Laboratory, and provide the student with experience in the use of benchtop instrumentation and in the realization and testing of circuits of general biomedical interest.

As concerns the teaching methods of this course unit, all students must attend Module 1, 2 [https://www.unibo.it/en/services-and-opportunities/health-and-assistance/health-and-safety/online-course-on-health-and-safety-in-study-and-internship-areas] on Health and Safety online.

Assessment methods

Student learning assessment will be performed through a final examination consisting of a written test, lasting 2 hours, followed by an oral examination (in the same day or the day after). During the written test, the students are not allowed to use books, notes, or informatic tools. The written test consists in questions and exercises; through the written test, the students demonstrate acquisition of the tools and methodologies to face problems concerning design and analysis of electromedical devices. The oral examination ascertains the theoretical skills and competences of the student, correctness of language, clearness of concepts and exposition.

Examination dates will be fixed on the basis of School calendar and will be published on Almaesami (https://almaesami.unibo.it/almaesami/welcome.htm ). Students can register for the examination only through the Almaesami service (https://almaesami.unibo.it/almaesami/welcome.htm ).

Teaching tools

Blackboard, document camera, notebook, projector, lecture notes, Biomedical Engineering Laboratory, Electronic and Telecommunication Laboratory, Matlab software

Office hours

See the website of Elisa Magosso


Good health and well-being Quality education

This teaching activity contributes to the achievement of the Sustainable Development Goals of the UN 2030 Agenda.