- Docente: Stefano Iotti
- Credits: 3
- SSD: BIO/12
- Language: English
- Teaching Mode: Traditional lectures
- Campus: Rimini
- Corso: Single cycle degree programme (LMCU) in Pharmacy (cod. 9078)
Learning outcomes
The student at the end of the course: - knows the biochemical and metabolic processes characteristic of the main organs, with references to the biochemical defects that underlie the corresponding metabolic diseases; - knows the different mechanisms of regulation and the different functionality of metabolic processes in different tissues; - acquires an overall vision of the metabolic homeostasis processes, introducing more advanced concepts such as process integration, control of complex systems and integration between reductionist and holistic approach. - learns the basic knowledge for the understanding of the thermodynamics of dissipative systems.
Course contents
Liver. Functions and metabolic flexibility. Glucidic metabolism. Lipid metabolism. Protein metabolism. Detossification of xenobiotics. Protection from Oxidative damage. Ethanol metabolism.
Muscle. Skeletal and cardiac muscle metabolism. Bioenergetics: system of energy buffers "phosphocreatine shuttle" model.
Tisuses homeostasis.
Regolatory mechanisms of tissues homeostasis. Regulation of transcription factors function. Hormones. Membrane receptors. Proteine kinases and signal transduction. G proteins.
Readings/Bibliography
biochemistry text books
D. Voet
J. Voet
C. W. Pratt
ZANICHELLI
specific scientific papers and handouts will be given by the teacherTeaching methods
frontal lessons
Assessment methods
WRITTEN TEST WITH 31 MULTIPLE-CHOICE QUESTIONS
Teaching tools
Teaching material such as slides, animations, films used during lessons will be made available to studens. The printable material should be taken by the student to class.
Office hours
See the website of Stefano Iotti