- Docente: Stefano Boschi
- Credits: 3
- SSD: CHIM/03
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Rimini
- Corso: Single cycle degree programme (LMCU) in Pharmacy (cod. 8414)
Learning outcomes
The students should acquire basic knowledge of radiochemistry, they should have a global overview of the production and quality control process of radiopharmaceuticals for research and clinical use.
The students should also learn the basic requirements concerning purity, safety and efficacy of radiopharmaceuticals as well as the role of quality assurance systems for the production of radiopharmaceuticals.
Course contents
Molecular Imaging : basic concepts regarding target selection and molecular probes
Radioactive decay: decay modes and relationships with radiopharmaceuticals
Nuclear Medicine and radiopharmaceuticals for SPECT and PET diagnostic and for therapeutic uses.
Tc-99m radiopharmaceuticals and SPECT imaging
Positron emitting radiopharmaceuticals and positron emission tomography (PET)
Brief outline of radiopharmaceuticals for radioimmunotherapy
PET radiopharmaceuticals: radiochemistry, preparation and their application in preclinical and clinical molecular imaging
F-18 labelled radiopharmaceuticals
Ga-68 labelled radiopharmaceuticals
Quality control of PET radiopharmaceuticals
Biochemistry and metabolism of PET radiopharmaceuticals
PET radiopharmaceuticals in preclinical molecular imaging and traslational researchl
Clinical molecular imaging and new perspectives in the development of radiopharmaceuticals
Quality assurance in radiopharmaceutical preparation
Radiopharmacy lay out
Regulatory and quality assurance systems for clinical and experimental radiopharmaceuticals (Italian regulation and GMP)
Readings/Bibliography
Paper copy of the slides, papers and review from literature and handouts
Teaching methods
Lectures, visit to a radiopharmacy
Assessment methods
Oral examination
Teaching tools
Computer, projector
Office hours
See the website of Stefano Boschi