- Docente: Roberto Gotti
- Credits: 3
- SSD: CHIM/08
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Rimini
- Corso: First cycle degree programme (L) in Quality Control of Health Products (cod. 0263)
Learning outcomes
The aim of the course is to provide the knowledge about analytical methods for quality control of cosmetics (both raw materials and formulations). In particular, attention will be paid to the aspects of stability and presence of impurities in cosmetic ingredients.
Course contents
Theory:
- The cosmetic laws in European Community.
- Quality control of cosmetic raw materials. Identification and quantitation of impurities (related substances). Stability of cosmetics.
- Chromatographic and electrokinetic methods in analysis of cosmetics. Analysis of allowed and banned ingredients.
- Sample preparation in analysis of cosmetics. Liquid-liquid extraction, solid phase extraction (SPE) solid phase microextraction (SPME). Supercritical fluid extraction, microwave assisted extraction.
- Applications of hyphenated techniques in the analysis of cosmetics: gas-chromatography mass-spectrometry (GC-MS), HPLC-diode array detection (DAD), capillary electrophoresis-mass spectrometry (CE-MS).
- Analytical profiles of the most important classes of cosmetics: sunscreens, hair colorants, surfactants, essential oils.
Lab activity:
- Sample preparation: liquid-liquid (L-L) and solid phase (SPE) extraction.
- HPLC analysis of forbidden and allowed ingredient in some cosmetics (tooth paste, hair colorants)
- TLC of hair colorants: identification of forbidden ingredients.
- GC of essential oils.
Readings/Bibliography
1) V. CAVRINI, V. ANDRISANO, Analisi Farmaceutica, Metodi di
riconoscimento e di separazione, Esculapio, 2004.
2) D. C. HARRIS, Chimica Analitica Quantitativa II Ed. Zanichelli,
2005.
3) Slides from lessons.
Teaching methods
The theoretical lessons and lab activity are intended to provide the knowledge of instrumental techniques used in cosmetic analysis.
Assessment methods
During the lab activity the students will carry out self-assessment experiments.
Final test will be by oral exposition on the subjects dealt in the course.
Teaching tools
Theoretical lessons will be held by using slides.
Lab activity: is available analytical instrumentation such as spectrophotometer, liquid and gas chromatographs (GC and HPLC) etc..
Office hours
See the website of Roberto Gotti