Sub-micrometer system comprising nanoparticles of magnesium

Sub-micrometer system comprising nanoparticles of magnesium in order to obtain a pharmaceutical formulation particularly suitable for administration to the body.

Title of the patent Sub-micrometer system comprising nanoparticles of magnesium, and process for its synthesis
Thematic area Chemistry and biotechnology
Ownership Alma Mater Studiorum - Università di Bologna
Inventors Mauro Comes Franchini, Erica Locatelli
Protection Italy
Licensing status Available for licensing agreement
Keywords Magnesium nanoparticles, photo thermal therapy, drug delivery, Alzheimer, nanomedicine
Filed on Feb 14, 2014

Magnesium is certainly the most biocompatible metal known.

It is also an essential element in the life of organisms, both plant and animal.

Currently, many biomedical components are made of magnesium, mainly because this metal is completely non-toxic for the organism and it can dissolve in biological fluids, thus also its possible presence in excess is not dangerous because it can be easily excreted via natural.

Some studies have highlighted the usefulness of the administration of magnesium in the treatment of certain diseases.

Polymeric nanocapsules made of a biodegradable and highly biocompatible synthetic polymer entrapping Mg nanoparticles.

  • Economical, simple and environmental friendly synthesis of magnesium nanoparticles and entrapment into biocompatible and FDA approved nano-micelles.
  • Possible application in diseases of the SNC (central nervous system) and photothermal cancer therapy