Foto del docente

Stefania Trazzi

Junior assistant professor (fixed-term)

Department of Biomedical and Neuromotor Sciences

Academic discipline: BIO/09 Physiology

Publications

Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E., Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons, «MOLECULAR NEUROBIOLOGY», 2020, 30, pp. 12035 - 12054 [Scientific article]

Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E., CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling, «BRAIN PATHOLOGY», 2019, 29, pp. 1 - 17 [Scientific article]

Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E., Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist, «FRONTIERS IN CELLULAR NEUROSCIENCE», 2019, 13, pp. 1 - 15 [Scientific article]

Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E., Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder, «NEUROPHARMACOLOGY», 2019, 27, pp. 107746 - 107764 [Scientific article]

Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*, CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2018, 27, pp. 1572 - 1592 [Scientific article]

Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, pp. 1 - 18 [Scientific article]

Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*, Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice, «EUROPEAN JOURNAL OF NEUROSCIENCE», 2018, 47, pp. 1054 - 1066 [Scientific article]

Guidi, Sandra; Bianchi, Patrizia; Stagni, Fiorenza; Giacomini, Andrea; Emili, Marco; Trazzi, Stefania; Ciani, Elisabetta; Bartesaghi, Renata, Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome, «CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS», 2017, 16, pp. 812 - 819 [Scientific article]

Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta, HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2016, 25(18), pp. 3887 - 3907 [Scientific article]

Stagni, F; Giacomini, A; Emili, M; Trazzi, S; Guidi, S; Sassi, M; Ciani, E; Rimondini, R; Bartesaghi, R, Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome, «NEUROSCIENCE», 2016, 333, pp. 277 - 301 [Scientific article]

Giacomini, Andrea; Stagni, Fiorenza; Trazzi, Stefania; Guidi, Sandra; Emili, Marco; Brigham, Elizabeth; Ciani, Elisabetta; Bartesaghi, Renata, Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 385 - 396 [Scientific article]

Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E., Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 298 - 310 [Scientific article]

Bianchi P; Bettini S; Guidi S; Ciani E; Trazzi S; Stagni F; Ragazzi E; Franceschini V; Bartesaghi R., Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome, «EXPERIMENTAL NEUROLOGY», 2014, 251, pp. 1 - 11 [Scientific article]

Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E, APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome., «NEUROBIOLOGY OF DISEASE», 2014, 67, pp. 24 - 36 [Scientific article]

Fuchs C;Trazzi S;Torricella R;Viggiano R;De Franceschi M;Amendola E;Gross C;Calzà L;Bartesaghi R;Ciani E, Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling., «NEUROBIOLOGY OF DISEASE», 2014, 70, pp. 53 - 68 [Scientific article]

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