Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Giuseppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta, Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, Article number: 5950 , pp. 1 - 24 [Scientific article]Open Access
Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali,
Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani, Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist, in: FENS 2020 e-Posters, 2020(atti di: FENS 2020, Virtual, 11-15 july 2020) [Poster]
Loi, M.; Trazzi, S.; Fuchs, C.; Galvani, G.; Medici, G.; Gennaccaro, L.; Tassinari, M.; Ciani, E., Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons, «MOLECULAR NEUROBIOLOGY», 2020, 57, pp. 2244 - 2262 [Scientific article]Open Access
Fuchs, C.; Gennaccaro, L.; Ren, E.; Galvani, G.; Trazzi, S.; Medici, G.; Loi, M.; Conway, E.; Devinsky, O.; Rimondini, R.; Ciani, E., Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder, «NEUROPHARMACOLOGY», 2020, 167, Article number: 107746 , pp. 1 - 18 [Scientific article]
Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E., CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019), «BRAIN PATHOLOGY», 2019, 29, pp. 658 - 674 [Scientific article]
Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E., Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist, «FRONTIERS IN CELLULAR NEUROSCIENCE», 2019, 13, Article number: 169 , pp. 1 - 15 [Scientific article]Open Access
Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*, CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2018, 27, pp. 1572 - 1592 [Scientific article]Open Access
Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, Article number: 9726950 , pp. 1 - 18 [Scientific article]Open Access
Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Martire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, pp. 1 - 18 [Scientific article]
Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*, Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice, «EUROPEAN JOURNAL OF NEUROSCIENCE», 2018, 47, pp. 1054 - 1066 [Scientific article]
Guidi, Sandra; Bianchi, Patrizia; Stagni, Fiorenza; Giacomini, Andrea; Emili, Marco; Trazzi, Stefania; Ciani, Elisabetta; Bartesaghi, Renata, Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome, «CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS», 2017, 16, pp. 812 - 819 [Scientific article]
Trazzi, Stefania; Fuchs, Claudia; Viggiano, ROCCHINA ASSUNTA; DE FRANCESCHI, Marianna; Valli, Emanuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; RIMONDINI GIORGINI, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta, HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2016, 25(18), pp. 3887 - 3907 [Scientific article]
Stagni, Fiorenza; Giacomini, Andrea; Emili, Marco; Trazzi, Stefania; Guidi, Sandra; Sassi, M; Ciani, Elisabetta; RIMONDINI GIORGINI, Roberto; Bartesaghi, Renata, Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome, «NEUROSCIENCE», 2016, 333, pp. 277 - 301 [Scientific article]
Giacomini, Andrea; Stagni, Fiorenza; Trazzi, Stefania; Guidi, Sandra; Emili, Marco; Brigham, Elizabeth; Ciani, Elisabetta; Bartesaghi, Renata, Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 385 - 396 [Scientific article]
Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E., Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 298 - 310 [Scientific article]
