Foto del docente

Stefania Trazzi

Associate Professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: BIOS-06/A Physiology

Publications

Stagni, Fiorenza; Giacomini, Andrea; Emili, Marco; Trazzi, Stefania; Guidi, Sandra; Sassi, M; Ciani, Elisabetta; RIMONDINI GIORGINI, Roberto; Bartesaghi, Renata, Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome, «NEUROSCIENCE», 2016, 333, pp. 277 - 301 [Scientific article]

Giacomini, Andrea; Stagni, Fiorenza; Trazzi, Stefania; Guidi, Sandra; Emili, Marco; Brigham, Elizabeth; Ciani, Elisabetta; Bartesaghi, Renata, Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 385 - 396 [Scientific article]

Fuchs, C.; Rimondini, R.; Viggiano, R.; Trazzi, S.; De Franceschi, M.; Bartesaghi, R.; Ciani, E., Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder, «NEUROBIOLOGY OF DISEASE», 2015, 82, pp. 298 - 310 [Scientific article]

Bianchi P; Bettini S; Guidi S; Ciani E; Trazzi S; Stagni F; Ragazzi E; Franceschini V; Bartesaghi R., Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome, «EXPERIMENTAL NEUROLOGY», 2014, 251, pp. 1 - 11 [Scientific article]

Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E, APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome., «NEUROBIOLOGY OF DISEASE», 2014, 67, pp. 24 - 36 [Scientific article]

Fuchs C;Trazzi S;Torricella R;Viggiano R;De Franceschi M;Amendola E;Gross C;Calzà L;Bartesaghi R;Ciani E, Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling., «NEUROBIOLOGY OF DISEASE», 2014, 70, pp. 53 - 68 [Scientific article]

Sandra Guidi;Fiorenza Stagni;Patrizia Bianchi;Elisabetta Ciani;Elena Ragazzi;Stefania Trazzi;Gabriele Grossi;Chiara Mangano;Laura Calzà;Renata Bartesaghi, Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome, «BRAIN PATHOLOGY», 2013, 23, pp. 129 - 143 [Scientific article]

VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E, CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells, «BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS», 2012, 1819, pp. 1173 - 1185 [Scientific article]

Fuchs C; Ciani E; Guidi S; Trazzi S; Bartesaghi R, Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression, «LABORATORY INVESTIGATION», 2012, 92, pp. 1648 - 1660 [Scientific article]

Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E., APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome., «HUMAN MOLECULAR GENETICS», 2011, 20, pp. 1560 - 1567 [Scientific article]

TRAZZI S.; STEGER M.; MITRUGNO V.M.; BARTESAGHI R.;CIANI E., CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/GSK-3{beta}/{beta}-catenin signaling, «THE JOURNAL OF BIOLOGICAL CHEMISTRY», 2010, 285, pp. 10098 - 10109 [Scientific article]

P. Bianchi; E. Ciani; S. Guidi; S. Trazzi; D. Felice; G. Grossi; M. Fernandez; A. Giuliani; L. Calza'; R. Bartesaghi, Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome, «THE JOURNAL OF NEUROSCIENCE», 2010, 30, pp. 8769 - 8779 [Scientific article]

Gopalakrishnan S.; Sullivan B. A.; Trazzi S.; Della Valle G.; Robertson K. D., DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions, «HUMAN MOLECULAR GENETICS», 2009, 18, pp. 3178 - 3193 [Scientific article]

FILA T; TRAZZI S; CROCHEMORE C; BARTESAGHI R; CIANI E., Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation., «THE JOURNAL OF BIOLOGICAL CHEMISTRY», 2009, 284, pp. 15325 - 15338 [Scientific article]

Trazzi S.; Perini G.; Bernardoni R.; Zoli M.; Reese J. C.; Musacchio A.; Della Valle G., The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation., «PLOS ONE», 2009, 4, Article number: e5832 , pp. 1 - 13 [Scientific article]Open Access

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