Foto del docente

Stefania Trazzi

Professoressa associata

Dipartimento di Scienze Biomediche e Neuromotorie

Settore scientifico disciplinare: BIO/09 FISIOLOGIA

Pubblicazioni

Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Martini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A., First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease, «ACS CHEMICAL NEUROSCIENCE», 2024, 15, pp. 2099 - 2111 [articolo]

Loi, Manuela; Bastianini, Stefano; Candini, Giulia; Rizzardi, Nicola; Medici, Giorgio; Papa, Valentina; Gennaccaro, Laura; Mottolese, Nicola; Tassinari, Marianna; Uguagliati, Beatrice; Berteotti, Chiara; Martire, Viviana Lo; Zoccoli, Giovanna; Cenacchi, Giovanna; Trazzi, Stefania; Bergamini, Christian; Ciani, Elisabetta, Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2023, 24, Article number: 5552, pp. 5552 - 5577 [articolo]Open Access

Tassinari, Marianna; Uguagliati, Beatrice; Trazzi, Stefania; Cerchier, Camilla Bruna; Cavina, Ottavia Vera; Mottolese, Nicola; Loi, Manuela; Candini, Giulia; Medici, Giorgio; Ciani, Elisabetta, Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder, «NEUROBIOLOGY OF DISEASE», 2023, 182, Article number: 106146, pp. 1 - 14 [articolo]Open Access

Mottolese, Nicola; Uguagliati, Beatrice; Tassinari, Marianna; Cerchier, Camilla Bruna; Loi, Manuela; Candini, Giulia; Rimondini, Roberto; Medici, Giorgio; Trazzi, Stefania; Ciani, Elisabetta, Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder, «BIOMOLECULES», 2023, 13, Article number: 1396, pp. 1 - 19 [articolo]Open Access

Brevetto n. ITPF7490WO, Artificial protein and its applications.

Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta, Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder, «NEUROTHERAPEUTICS», 2022, 19, pp. 1886 - 1904 [articolo]Open Access

Tassinari, Marianna; Mottolese, Nicola; Galvani, Giuseppe; Ferrara, Domenico; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Candini, Giulia; Rimondini, Roberto; Ciani, Elisabetta; Trazzi, Stefania, Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2022, 23, Article number: 8719, pp. 1 - 23 [articolo]Open Access

Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani, A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder, «NEUROBIOLOGY OF DISEASE», 2021, 153, Article number: 105304, pp. 1 - 10 [articolo]Open Access

Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvani G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E., Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death, «AGING AND DISEASE», 2021, 12, pp. 764 - 785 [articolo]Open Access

Nicola Mottolese, Giuseppe Galvani, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassinari, Stefania Trazzi, Elisabetta Ciani, Inhibition of microglia over-activation restores neuronal survival and maturation in a mouse model of CDKL5 deficiency disorder, in: N. Mottolese, G. Galvani, L. Gennaccaro, M. Loi, G. Medici, M. Tassinari, S. Trazzi, E. Ciani, Proceedings NWG 2021, 2021(atti di: Göttingen Meeting of the German Neuroscience Society, Göttingen, German, 2021) [atti di convegno-poster]

Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari, Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania, Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder, «JOURNAL OF NEUROINFLAMMATION», 2021, 18, Article number: 155, pp. 1 - 21 [articolo]Open Access

Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Giuseppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta, Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, Article number: 5950, pp. 1 - 24 [articolo]Open Access

Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani, Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist, in: FENS 2020 e-Posters, 2020(atti di: FENS 2020, Virtual, 11-15 july 2020) [atti di convegno-poster]

Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E., Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons, «MOLECULAR NEUROBIOLOGY», 2020, 30, pp. 12035 - 12054 [articolo]

Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E., Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder, «NEUROPHARMACOLOGY», 2020, 167, Article number: 107746, pp. 107746 - 107764 [articolo]

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