Stefania Falfari

THESIS TOPICS:

MECHANICAL / ENERGY ENGINEERING:

- Implementation of a 0D numerical model (python / matlab) of a bench for the characterization of the distillation properties of biofuels

- Implementation of a 0D numerical model (python) for the simulation of the thermo-fluid dynamic behavior of an internal combustion engine operating at low temperature

- Implementation of a virtual bench (python) for the characterization of anti-knock indices of biofuels

- Evolution of a numerical model (python) for the study of the lubricant-fuel-piston ring interaction in internal combustion engines for the assessment of the risk of pre-ignition

- Numerical-experimental study of innovative ignition systems for internal combustion engines

- 3D CFD analysis of the partialized performance of a positive ignition engine equipped with a passive pre-chamber

- 3D CFD analysis of the behavior of a positive ignition engine fueled with hydrogen gas based mixtures

- Methodological comparison between phenomenological and detailed chemistry combustion models implemented in a 3D CFD code for internal combustion engines

- Modeling of the notional nozzle for gaseous fuels (hydrogen for instance)

- Experimental validation of spray and wallfilm formation models with the FIRE M code

B2081 - CARDIOVASCULAR COMPUTATIONAL SIMULATION M (Component of the integrated course B2078 - CARDIOVASCULAR BIOMECHANICS M C.I.)


In collaboration with DEI:


1. CFD simulations with atrial dynamics to evaluate the leakage of a left atrial appendage occlusion device:


The thesis proposal aims to evaluate the hemodynamic condition of the left atrium and the left atrium in the presence of a leakage of the device. The objective is to analyze the flow around the occlusion device to evaluate the risk of thrombus formation, a crucial aspect for the safety and effectiveness of these implants. The work involves the creation of anatomical models of the left atrium, both with and without the device, followed by the execution of numerical simulations. The subsequent analysis will focus on the distribution of velocities and the identification of any stasis zones, with the possibility of comparing the results with other studies.


2. Calculation of thrombin concentration in the left atrium and auricle


The thesis proposal aims to develop a numerical model describing the generation and diffusion of thrombin in the blood, with an approach based on the resolution of partial differential equations. The project involves the implementation of the mathematical formulation of thrombin kinetics within a CFD solver, allowing to evaluate the thrombotic risk in different configurations. The application of this model could be useful for the study of thrombogenicity in conditions of atrial fibrillation and/or in the presence of medical devices (see auricle occlusion).


In collaboration with some cardiologists:


Numerical modeling thesis (0D and 3D CFD model) of the hemodynamics of sections of the cardiovascular system in healthy / sick / operated patients.