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Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Coordinatrice del Corso di Laurea Magistrale a ciclo unico in Chimica e tecnologia farmaceutiche

Pubblicazioni

Ruolo editoriale nella rivista «Journal of Medicinal Chemistry»

Uliassi, Elisa; Pena-Altamira, Luis Emiliano; Morales, Aixa V.; Massenzio, Francesca; Petralla, Sabrina; Rossi, Michele; Roberti, Marinella; Martinez Gonzalez, Loreto; Martinez, Ana; Monti, Barbara; Bolognesi, Maria Laura*, A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential, «ACS CHEMICAL NEUROSCIENCE», 2019, 10, pp. 279 - 294 [articolo]

Ramsay, Rona R; Popovic-Nikolic, Marija R; Nikolic, Katarina; Uliassi, Elisa; Bolognesi, Maria Laura, A perspective on multi-target drug discovery and design for complex diseases, «CLINICAL AND TRANSLATIONAL MEDICINE», 2018, 7, pp. 1 - 14 [articolo]

Prati, Federica; Bottegoni, Giovanni; Bolognesi, Maria Laura; Cavalli, Andrea, BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease, «JOURNAL OF MEDICINAL CHEMISTRY», 2018, 61, pp. 619 - 637 [articolo]

Uliassi, Elisa; Piazzi, Lorna; Belluti, Federica; Mazzanti, Andrea; Kaiser, Marcel; Brun, Reto; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura*, Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections, «CHEMMEDCHEM», 2018, 13, pp. 678 - 683 [articolo]

Elisi, Gian Marco; Santucci, Matteo; D'Arca, Domenico; Lauriola, Angela; Marverti, Gaetano; Losi, Lorena; Scalvini, Laura; Bolognesi, Maria Laura; Mor, Marco; Costi, Maria Paola, Repurposing of Drugs Targeting YAP-TEAD Functions, «CANCERS», 2018, 10, pp. 1 - 19 [articolo]

Chioua, Mourad; Buzzi, Eleonora; Moraleda, Ignacio; Iriepa, Isabel; Maj, Maciej; Wnorowski, Artur; Giovannini, Catia; Tramarin, Anna; Portali, Federica; Ismaili, Lhassane; López-Alvarado, Pilar; Bolognesi, Maria Laura; Jóźwiak, Krzysztof; Menéndez, J. Carlos; Marco-Contelles, José; Bartolini, Manuela*, Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2018, 155, pp. 839 - 846 [articolo]

Gandini, Annachiara; Bartolini, Manuela; Tedesco, Daniele; Martinez-Gonzalez, Loreto; Roca, Carlos; Campillo, Nuria E.; Zaldivar-Diez, Josefa; Perez, Concepción; Zuccheri, Giampaolo; Miti, Andrea; Feoli, Alessandra; Castellano, Sabrina; Petralla, Sabrina; Monti, Barbara; Rossi, Martina; Moda, Fabio; Legname, Giuseppe; Martinez, Ana; Bolognesi, Maria Laura*, Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors, «JOURNAL OF MEDICINAL CHEMISTRY», 2018, 61, pp. 7640 - 7656 [articolo]

Ortuso, Francesco*; Bagetta, Donatella; Maruca, Annalisa; Talarico, Carmine; Bolognesi, Maria L.; Haider, Norbert; Borges, Fernanda; Bryant, Sharon; Langer, Thierry; Senderowitz, Hanoch; Alcaro, Stefano, The Mu.Ta.Lig. Chemotheca: A community-populated molecular database for multi-target ligands identification and compound-repurposing, «FRONTIERS IN CHEMISTRY», 2018, 6, pp. 1 - 6 [articolo]

Terra, Bruna S.; Da Silva, Pedro H. C.; Tramarin, Anna; Franco, Lucas L.; Da Cunha, Elaine F. F.; Macedo, Fernando; Ramalho, Teodorico C.; Bartolini, Manuela; Bolognesi, Maria L.; De Fátima, Ângelo, Two novel donepezil-lipoic acid hybrids: Synthesis, anticholinesterase and antioxidant activities and theoretical studies, «JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY», 2018, 29, pp. 738 - 747 [articolo]

Uliassi, Elisa; Fiorani, Giulia; Krauth-Siegel, R. Luise; Bergamini, Christian; Fato, Romana; Bianchini, Giulia; Carlos Menéndez, J.; Molina, Maria Teresa; López-Montero, Eulogio; Falchi, Federico; Cavalli, Andrea; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura, Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 141, pp. 138 - 148 [articolo]

Gandini, Annachiara; Prati, Federica; Uliassi, Elisa; Bolognesi, Maria L., Drug Discovery Strategies for the Generation of Multitarget Ligands against Neglected Tropical Diseases, in: Drug Selectivity: An Evolving Concept in Medicinal Chemistry, Weinheim, Wiley‐VCH Verlag GmbH & Co. KGaA, 2017, pp. 135 - 159 (METHODS AND PRINCIPLES IN MEDICINAL CHEMISTRY) [capitolo di libro]

Bolognesi, M.L.*, From Imaging Agents to Theranostic Drugs in Alzheimer's Disease, in: Bolognesi, M.L.*, Comprehensive Medicinal Chemistry III, Amsterdam, Elsevier Inc., 2017, pp. 74 - 106 [capitolo di libro]

Uliassi, Elisa; Prati, Federica; Bongarzone, Salvatore; Bolognesi, Maria Laura, Medicinal Chemistry of Hybrids for Neurodegenerative Diseases, in: Uliassi, Elisa*, Design of Hybrid Molecules for Drug Development, oxford, Elsevier Inc., 2017, pp. 259 - 277 [capitolo di libro]

Huryn, Donna M.; Bolognesi, Maria Laura; Young, Wendy B., Medicinal Chemistry: Where Are All the Women?, «ACS MEDICINAL CHEMISTRY LETTERS», 2017, 8, pp. 900 - 902 [articolo]