Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Coordinatrice del Corso di Laurea Magistrale a ciclo unico in Chimica e tecnologia farmaceutiche

Pubblicazioni

Bolognesi ML; Bartolini M ; Mancini F ; Chiriano G ; Ceccarini L; Rosini M; Milelli A; Tumiatti V; Andrisano V; Melchiorre C, Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities, «CHEMMEDCHEM», 2010, 5, pp. 1215 - 1220 [articolo]

Cavalli A; Lizzi F ; Bongarzone S ; Belluti F; Piazzi L ; Bolognesi ML, Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates, «FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY», 2010, 58, pp. 51 - 60 [articolo]

E. Simoni; M. Rosini; C. Bergamini; R. Fato; M.L. Bolognesi; A. Cavalli; R. Motterlini; G. Lenaz; C. Melchiorre, Curcumin analogs as multi-target antioxidants: focus on mitochondria., in: Trekking through receptor chemistry, S. L., s. n., 2010, pp. 108 - 108 (atti di: 28th Camerino-Cyprus-Noordwijkerhout Symposium, Camerino-Italy, May, 16-20, 2010) [atti di convegno-abstract]

ML Bolognesi, DESIGN OF BIFUNCTIONAL SMALL MOLECULES MODULATING PROTEIN-PROTEIN INTERACTIONS IN PRION DISEASES, in: XX National Meeting on Medicinal Chemistry, s.l, s.n, 2010, pp. 18 - 18 (atti di: XX National Meeting on Medicinal Chemistry, Abano, Italy, September, 12-16, 2010) [atti di convegno-abstract]

M. L. Bolognesi; A. Minarini; C. Melchiorre, Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease, in: Emerging Drugs and Targets for Alzheimer’s Disease Volume 2: Neuronal Plasticity, Neuronal Protection and Other Miscellaneous Strategies, CAMBRIDGE, Royal Society of Chemistry, 2010, pp. 213 - 226 (RSC Drug Discovery Series) [capitolo di libro]

Bolognesi ML; Tran HNA ; Staderini M ; Monaco A ; Lopez-Cobenas A ; Bongarzone S ; Biarnes X ; Lopez-Alvarado P; Cabezas N; Caramelli M; Carloni P; Menendez JC; Legname G, Discovery of a Class of Diketopiperazines as Antiprion Compounds, «CHEMMEDCHEM», 2010, 5, pp. 1324 - 1334 [articolo]

ML Bolognesi, From target-based to multi-target-based drug design approaches for neglected tropical diseases, in: Program and Abstracts Proteine 2010, s.l, s.n, 2010, pp. O-11 - O-11 (atti di: Proteine 2010, Parma, Italy, 8-10 April 2010) [atti di convegno-abstract]

M. Rosini; E. Simoni; M. L. Bolognesi; C. Bergamini; R. Fato; G. Lenaz; C. Melchiorre, Mitochondria-directed antioxidants in Alzheimer's disease., in: Final program and poster abstracts for the 11th international Geneva/Springfield symposium on advances in Alzheimer therapy, S. L., s. n., 2010, pp. 75 - 75 (atti di: 11th international Geneva/Springfield symposium on advances in Alzheimer therapy, Geneva, Switzerland, March, 24-27, 2010) [atti di convegno-abstract]

ML Bolognesi; M. Bartolini; F. Mancini; G. Chiriano; L. Ceccarini; M. Rosini; A. Milelli; V. Tumiatti; V. Andrisano; C. Melchiorre, Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities, in: Trekking through receptor chemistry, s.l, s.n, 2010, pp. 124 - 124 (atti di: 28th Camerino-Cyprus-Noordwijkerhout symposium, Camerino (MC), 16-20 maggio 2010) [atti di convegno-abstract]

C Melchiorre; ML Bolognesi, POLYPHARMACOLOGY: CREATING SELECTIVE NON-SELECTIVITY, in: Trekking through Receptor Chemistry, s.l, s.n, 2010, pp. 25 - 25 (atti di: 28th Camerino-Cyprus-Noordwijkerhout Symposium, Camerino, Italy, May, 16-20, 2010) [atti di convegno-abstract]

Bongarzone S; Tran HN; Cavalli A; Roberti M; Carloni P; Legname G; Bolognesi ML., Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound., «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 8197 - 81201 [articolo]

Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L.; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C., Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents., «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 7264 - 7268 [articolo]

Melchiorre C; Bolognesi ML; Minarini A; Rosini M ; Tumiatti V, Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy, «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 5906 - 5914 [articolo]

ML Bolognesi; M Rosini; A Minarini; V Tumiatti; A Cavalli; M Bartolini; V Andrisano; R Fato; C Bergamini; C Melchiorre, Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks, in: Final Program and Poster Abstractsfor the 11th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, s.l, s.n, 2010, pp. 93 - 93 (atti di: 11th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, Geneva, Switzerland, March, 24-27, 2010) [atti di convegno-abstract]

Tran HNA; Bongarzone S ; Carloni P; Legname G ; Bolognesi ML, Synthesis and evaluation of a library of 2,5-bisdiamino-benzoquinone derivatives as probes to modulate protein-protein interactions in prions, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2010, 20, pp. 1866 - 1868 [articolo]