Foto del docente

Maria Laura Bolognesi

Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Director of Single Cycle Degree of Chemistry and Pharmaceutical Technologies

Publications

Prati, Federica; Bottegoni, Giovanni; Bolognesi, Maria Laura; Cavalli, Andrea, BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease, «JOURNAL OF MEDICINAL CHEMISTRY», 2018, 61, pp. 619 - 637 [Scientific article]

Terra, Bruna S.; Da Silva, Pedro H. C.; Tramarin, Anna; Franco, Lucas L.; Da Cunha, Elaine F. F.; Macedo, Fernando; Ramalho, Teodorico C.; Bartolini, Manuela; Bolognesi, Maria L.; De Fátima, Ângelo, Two novel donepezil-lipoic acid hybrids: Synthesis, anticholinesterase and antioxidant activities and theoretical studies, «JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY», 2018, 29, pp. 738 - 747 [Scientific article]

Uliassi, Elisa; Fiorani, Giulia; Krauth-Siegel, R. Luise; Bergamini, Christian; Fato, Romana; Bianchini, Giulia; Carlos Menéndez, J.; Molina, Maria Teresa; López-Montero, Eulogio; Falchi, Federico; Cavalli, Andrea; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura, Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 141, pp. 138 - 148 [Scientific article]

Uliassi, Elisa; Prati, Federica; Bongarzone, Salvatore; Bolognesi, Maria Laura, Medicinal Chemistry of Hybrids for Neurodegenerative Diseases, in: Uliassi, Elisa*, Design of Hybrid Molecules for Drug Development, oxford, Elsevier Inc., 2017, pp. 259 - 277 [Chapter or essay]

Huryn, Donna M.; Bolognesi, Maria Laura; Young, Wendy B., Medicinal Chemistry: Where Are All the Women?, «ACS MEDICINAL CHEMISTRY LETTERS», 2017, 8, pp. 900 - 902 [Scientific article]

Bruno, Stefano; Uliassi, Elisa; Zaffagnini, Mirko; Prati, Federica; Bergamini, Christian; Amorati, Riccardo; Paredi, Gianluca; Margiotta, Marilena; Conti, Paola; Costi, Maria Paola; Kaiser, Marcel; Cavalli, Andrea; Fato, Romana; Bolognesi, Maria Laura, Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule, «CHEMICAL BIOLOGY & DRUG DESIGN», 2017, 89, pp. 1 - 11 [Scientific article]

Bolognesi, Maria Laura, Neurodegenerative drug discovery: Building on the past, looking to the future, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 707 - 709 [Comment or similar]

Uliassi, Elisa; Gandini, Annachiara; Perone, Rosaria Carmela; Bolognesi, Maria Laura, Neuroregeneration versus neurodegeneration: Toward a paradigm shift in Alzheimer's disease drug discovery, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 995 - 1013 [Scientific article]

Roldán-Peña, Jesús M.; Alejandre-Ramos, Daniel; López, O“scar; Maya, Inés; Lagunes, Irene; Padrón, José M.; Peña-Altamira, Luis Emiliano; Bartolini, Manuela; Monti, Barbara; Bolognesi, Maria L.; Fernández-Bolaños, José G., New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 138, pp. 761 - 773 [Scientific article]

Peña-Altamira, E; Petralla, S; Massenzio, F; Virgili, M; Bolognesi, Ml; Monti, B., Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease., «FRONTIERS IN AGING NEUROSCIENCE», 2017, 9, pp. 1 - 15 [Scientific article]

Jeřábek, Jakub; Uliassi, Elisa; Guidotti, Laura; Korábečný, Jan; Soukup, Ondřej; Sepsova, Vendula; Hrabinova, Martina; Kuča, Kamil; Bartolini, Manuela; Peña-Altamira, Luis Emiliano; Petralla, Sabrina; Monti, Barbara; Roberti, Marinella; Bolognesi, Maria Laura, Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 127, pp. 250 - 262 [Scientific article]

Gandini, Annachiara; Bolognesi, Maria Laura, Therapeutic Approaches to Prion Diseases, in: Gandini, Annachiara, Progress in Molecular Biology and Translational Science, Cambridge, Elsevier B.V., 2017, pp. 433 - 453 [Chapter or essay]

Chacón-Vargas, Karla Fabiola; Nogueda-Torres, Benjamin; Sánchez-Torres, Luvia E.; Suarez-Contreras, Erick; Villalobos-Rocha, Juan Carlos; Torres-Martinez, Yuridia; Lara-Ramirez, Edgar E.; Fiorani, Giulia; Krauth-Siegel, R Luise; Bolognesi, Maria Laura; Monge, Antonio; Rivera, Gildardo, Trypanocidal activity of quinoxaline 1,4 Di-N-oxide derivatives as trypanothione reductase inhibitors, «MOLECULES», 2017, 22, pp. 220 - 220 [Scientific article]

Lemes, Laís Flávia Nunes; De Andrade Ramos, Giselle; De Oliveira, Andressa Souza; Da Silva, Fernanda Motta R.; De Castro Couto, Gina; Da Silva Boni, Marina; Guimarães, Marcos Jorge R.; Souza, Isis Nem O.; Bartolini, Manuela; Andrisano, Vincenza; Do Nascimento Nogueira, Patrícia Coelho; Silveira, Edilberto Rocha; Brand, Guilherme D.; Soukup, Ondřej; Korábečný, Jan; Romeiro, Nelilma C.; Castro, Newton G.; Bolognesi, Maria Laura; Romeiro, Luiz Antonio Soares, Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2016, 108, pp. 687 - 700 [Scientific article]

Peña-Altamira, E; Prati, F; Massenzio, F; Virgili, M; Contestabile, A; Bolognesi, Ml; Monti, B., Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation., «EXPERT OPINION ON THERAPEUTIC TARGETS», 2016, 20, pp. 627 - 640 [Scientific article]