Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Coordinatrice del Corso di Dottorato in Scienze biotecnologiche, biocomputazionali, farmaceutiche e farmacologiche

Pubblicazioni

Bolognesi, Maria Laura, Neurodegenerative drug discovery: Building on the past, looking to the future, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 707 - 709 [replica/breve intervento]

Uliassi, Elisa; Gandini, Annachiara; Perone, Rosaria Carmela; Bolognesi, Maria Laura*, Neuroregeneration versus neurodegeneration: Toward a paradigm shift in Alzheimer's disease drug discovery, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 995 - 1013 [articolo]

Roldán-Peña, Jesús M.; Alejandre-Ramos, Daniel; López, O“scar; Maya, Inés; Lagunes, Irene; Padrón, José M.; Peña-Altamira, Luis Emiliano; Bartolini, Manuela; Monti, Barbara; Bolognesi, Maria L.; Fernández-Bolaños, José G., New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 138, pp. 761 - 773 [articolo]

Peña-Altamira, E; Petralla, S; Massenzio, F; Virgili, M; Bolognesi, Ml; Monti, B., Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease., «FRONTIERS IN AGING NEUROSCIENCE», 2017, 9, pp. 1 - 15 [articolo]

Jeřábek, Jakub; Uliassi, Elisa; Guidotti, Laura; Korábečný, Jan; Soukup, Ondřej; Sepsova, Vendula; Hrabinova, Martina; Kuča, Kamil; Bartolini, Manuela; Peña-Altamira, Luis Emiliano; Petralla, Sabrina; Monti, Barbara; Roberti, Marinella; Bolognesi, Maria Laura, Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 127, pp. 250 - 262 [articolo]

Gandini, Annachiara; Bolognesi, Maria Laura*, Therapeutic Approaches to Prion Diseases, in: Gandini, Annachiara, Progress in Molecular Biology and Translational Science, Cambridge, Elsevier B.V., 2017, pp. 433 - 453 [capitolo di libro]

Chacón-Vargas, Karla Fabiola; Nogueda-Torres, Benjamin; Sánchez-Torres, Luvia E.; Suarez-Contreras, Erick; Villalobos-Rocha, Juan Carlos; Torres-Martinez, Yuridia; Lara-Ramirez, Edgar E.; Fiorani, Giulia; Krauth-Siegel, R Luise; Bolognesi, Maria Laura; Monge, Antonio; Rivera, Gildardo, Trypanocidal activity of quinoxaline 1,4 Di-N-oxide derivatives as trypanothione reductase inhibitors, «MOLECULES», 2017, 22, pp. 220 - 220 [articolo]

Lemes, Laís Flávia Nunes; De Andrade Ramos, Giselle; De Oliveira, Andressa Souza; Da Silva, Fernanda Motta R.; De Castro Couto, Gina; Da Silva Boni, Marina; Guimarães, Marcos Jorge R.; Souza, Isis Nem O.; Bartolini, Manuela; Andrisano, Vincenza; Do Nascimento Nogueira, Patrícia Coelho; Silveira, Edilberto Rocha; Brand, Guilherme D.; Soukup, Ondřej; Korábečný, Jan; Romeiro, Nelilma C.; Castro, Newton G.; Bolognesi, Maria Laura; Romeiro, Luiz Antonio Soares, Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2016, 108, pp. 687 - 700 [articolo]

Peña-Altamira, E; Prati, F; Massenzio, F; Virgili, M; Contestabile, A; Bolognesi, Ml; Monti, B., Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation., «EXPERT OPINION ON THERAPEUTIC TARGETS», 2016, 20, pp. 627 - 640 [articolo]

Bolognesi, Maria Laura; Gandini, Annachiara; Prati, Federica; Uliassi, Elisa, From Companion Diagnostics to Theranostics: A New Avenue for Alzheimer's Disease?, «JOURNAL OF MEDICINAL CHEMISTRY», 2016, 59, pp. 7759 - 7770 [articolo]

Bolognesi, Maria Laura; Cavalli, Andrea, Multitarget Drug Discovery and Polypharmacology, «CHEMMEDCHEM», 2016, 11, pp. 1190 - 1192 [replica/breve intervento]

Prati, Federica; Cavalli, Andrea; Bolognesi, Maria Laura, Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease, «MOLECULES», 2016, 21, pp. 466 - 466 [articolo]

Prati, Federica; Bergamini, Christian; Fato, Romana; Soukup, Ondrej; Korabecny, Jan; Andrisano, Vincenza; Bartolini, Manuela; Bolognesi, Maria Laura, Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease, «CHEMMEDCHEM», 2016, 11, pp. 1284 - 1295 [articolo]

Silva, Renata Oliveira; de Oliveira, Andressa Souza; Nunes Lemes, Laís Flávia; de Camargo Nascente, Luciana; Coelho do Nascimento Nogueira, Patrícia; Silveira, Edilberto R.; Brand, Guilherme D.; Vistoli, Giulio; Cilia, Antonio; Poggesi, Elena; Buccioni, Michela; Marucci, Gabriella; Bolognesi, Maria Laura; Romeiro, Luiz Antonio Soares, Synthesis and structure–activity relationships of novel arylpiperazines as potent antagonists of α1-adrenoceptor, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2016, 122, pp. 601 - 610 [articolo]

Bolognesi, Maria Laura; Legname, Giuseppe, Approaches for discovering anti-prion compounds: Lessons learned and challenges ahead, «EXPERT OPINION ON DRUG DISCOVERY», 2015, 10, pp. 389 - 397 [articolo]