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00351 - Pharmacology

Academic Year 2018/2019

                
                        Docente:
                        Alberto Vaccheri
                    
                        Credits:
                        2
                    
                        SSD:
                        BIO/14
                    
                        Language:
                        Italian
                    
                        Moduli:
                        
                            Alberto Vaccheri
                            (Modulo 1)
                        
                            Domenico Motola
                            (Modulo 2)
                        
                        Teaching Mode:
                        
                                    Traditional lectures (Modulo 1)
                                
                                    Traditional lectures (Modulo 2)
                                
                            Campus:
                            Bologna
                        
                            Corso:
                            First cycle degree programme (L) in
                            Orthopaedics techniques (cod. 8483)

                            Teaching resources on Virtuale

Learning outcomes

The course provides knowledge of the basic principles of pharmacology, with special attention to drugs of CNS, inflammation, pain, musculo-skeletal system

Course contents

Pharmacokinetics: absorption, distribution, metabolism and elimination of drugs

Main pharmacokinetic parameters: bioavailability, volume of distribution, AUC, Cmax, Tmax, clearance)

Pharmacodynamics: mechanisms of drug action, agonists, antagonists, relation between drug concentration and effect

Drug-drug interactions

Drug toxicityi: classification of adverse drug reactions and principles of post-marketing drug surveillance

General principles of drug use in pregnancy, paediatrics, geriatrics

Drugs acting on the central nervous system

Basics of hypnotics and sedatives, antipsychotics, antidepressants and antiepileptics

Opioid analgesics, Local anesthetics, Drugs for spasticity

Drug therapy of inflammation

Non steroidal antiiflammatory drugs (NSAIDs) and paracetamol; Antiinflammatory corticosteroids

General principles of pain therapy

Drugs og bllod coagulation

Antiplatelet drugs, Heparines, Vitamin K antagonists, DOACs

Antimicrobial chemotherapy

General principles of antimicrobial chemotherapy; Antimicrobial agents: antibacterial and antifungal agents

Readings/Bibliography

Cella SG, Di Giulio AM, Gorio A, Scaglione F, Farmacologia generale e speciale per le lauree sanitarie, Piccin ed, 2010.

Waller D.G., Renwick A.G., Hillier K. FARMACOLOGIA MEDICA ED ELEMENTI DI TERAPIA. (Ediz. Italiana) Elsevier, Milano, 2011.

Teaching methods

Lectures

Assessment methods

Questionnaire consisting of 40 multiple choice questions

Teaching tools

Teaching material (access restricted to UNIBO student) can be downloaded at:https://iol.unibo.it

Office hours

See the website of Alberto Vaccheri

See the website of Domenico Motola