- Docente: Giovanni Valdrè
- Credits: 6
- SSD: ING-IND/34
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Cesena
- Corso: First cycle degree programme (L) in Biomedical Engineering (cod. 0946)
Learning outcomes
Knowledge of the physical, chemical, biological and engineering properties of biomaterials
Specific applications of Biomaterials
Course contents
- Introduction and Definitions
- Panorama of general applications of biomaterials
- Elements of Design of Biomaterials
- Definition of Biocompatibility
- The Frontier of Research: biomimetic materials and tissue engineering
- Body reaction and response to material implantation
- Introduction
- Elements of Biology
- The tissue healing process
- Tissue response to material implantation
- Blood response, hemocompatibility
- Structure and properties of materials
- The solid state and chemical bonds in solids
- The definition of phase
- Basics of thermodynamics and phase stability
- Principles of crystallography
- Order-disorder transitions
- Defects in solids
- Structure-property relationships
- Structural and analytical methodologies for the characterization of biomaterials
- Mechanical properties
- Hardness, friction, wear
- Thermal, electrical and acoustic properties
- X-ray absorption, density and porosity
- Bone, enamel and dentine permeability
- Optical properties
- Metallic Biomaterials
- Structure and properties of metals
- Phase diagrams
- Stainless steels, CoCr, Titanium alloys, gold and noble metal alloys, NiTi, and Shape Memory Alloys
- Application of metals
- Biocorrosion, Pourbaix diagrams
- Production processes
- Ceramic Biomaterials
- Structure and properties of ceramics
- Bioinert, biodegradable and bioactive ceramics
- Application of ceramics
- Carbon
- Production processes
- Biominerals
- Biological tissues
- Human hard tissues
- Hydroxyapatites
- Human soft tissues
- Collagen and elastin
- Tissue-derived biomaterials
- Preparation procedures
- Synthetic polymers
- The polymerization processes
- Structure and texture of polymers
- Glass transition
- Thermoplastic and thermohardening polymers
- Structure property relationships
- Biocompatibility
- Production processes
- Composite biomaterials
- Prostheses
- Biocompatibility tests
- Regulation and trading of biomaterials
Readings/Bibliography
RECOMANDED READING
C.Di Bello, Biomateriali, Pàtron Editore, Bologna
R.Pietrabissa, Biomateriali per protesi e organi artificiali, Pàtron Editore, Bologna
G.Valdrè, U.Valdrè, Misure e complementi di fisica, CLUEB, Bologna
A.F.von Recum, Handbook of Biomaterials Evaluation, Taylor &
Francis, London
Assessment methods
Oral Examination
Teaching tools
Experiments
Links to further information
Office hours
See the website of Giovanni Valdrè