- Docente: Ester Speroni
- Credits: 7
- SSD: BIO/14
- Language: Italian
- Moduli: Ester Speroni (Modulo 1) Ester Speroni (Modulo 2)
- Teaching Mode: Traditional lectures (Modulo 1) Traditional lectures (Modulo 2)
- Campus: Bologna
- Corso: Long cycle 2nd degree programme in Pharmacy (cod. 0039)
Course contents
Course contents: GENERAL PHARMACOLOGY. General pharmacokinetics: movement of drugs across cell membranes; routes of administration and absorption; bioavailability; distribution of drugs in the body; volume of distribution, binding to plasma proteins; drug metabolism; excretion; time-course of drug plasmatic contents (after single or repeated administration). General pharmacodynamics: targets and mechanisms of drug action; dose-response curve; agonists, partial agonists, antagonists; individual variations (effects of age, pathological states, drug interactions, tolerance, placebo effects). General toxicity: side-effects, overdose, idiosyncratic and allergic reactions; teratogenesis and foetal toxicity; carcinogenesis; drug dependency. Clinical evaluation. Pharmacosurveillance and plant drug monitoring.
Definition and aim of PHARMACOGNOSY; definition and classification of plant drug; factors affecting the activity: natural, endogenous, exogenous and preparation-dependent. Plant drug: conditions of preservation, analysis, identification, quality control, distinctive characters, endogenous active substances, therapeutic strategies, toxic effects, potion preparation of the following PLANT DRUGS: containing carbohydrates: Manna*, Starch, Hollyhock, Flax*, Agar, Arabic Gum*; Tragacanth Gum*, Cotton. containing lipids: Castor oil*, Cacao butter. containing essential oils and gums: Wormwood, Matricaria*, Roman Chamomile*, Cannabis, Camphor, Capsicum*, Fish (or Levant) Berry, Eucalyptus*, Male fern*, Clove*, Mint, Nutmeg, Valerian*. containing tannins: Witch hazel*. containing quinones: Aloe*, Cascara sagrada*, , Buckthorn*, Senna*, Rhubarb*, Saint John's wort. containing saponins: Licorice*, Ginseng. containing cardiac glycosides: Foxgloves*, Strophanthus*, .Squill. containing flavonoid glycosides: Maidenhair tree. containing alkaloids: Opium poppy, Boldo*, Ipacacuanha*, Cinchona*, Rauwolfia, containing xanthines: (Cacao, Coffee, Tea), Tobacco, Nux vomica*, Ergot of Rye*, Ephedras, Jaborandi, Calabar bean, Deadly nightshade*, Henbane, Thorn apple, Coca, Curare, Common periwinkle, Yew. Plant drugs containing psychotomimetic substances. DRUGS FROM ANIMALS: sera, vaccines.
Office hours
See the website of Ester Speroni