Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Coordinatrice del Corso di Dottorato in Scienze biotecnologiche, biocomputazionali, farmaceutiche e farmacologiche

Pubblicazioni

Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchiorre C., Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 7883 - 7886 [articolo]

M. L. Bolognesi, Two medicinal chemistry driven approaches toward new antitrypanosomal and antileishmanial agents, in: www.esf.org/conferences/09277, s.l, s.n, 2009, pp. xx - yy (atti di: ESF Research Conferences: Europe-Africa Frontier Research Conference Series INFECTIOUS DISEASES: FROM BASIC TO TRANSLATIONAL RESEARCH, Cape Town, South Africa, 4 - 9 April 2009) [Contributo in Atti di convegno]

C. Mangano; N. Calonghi; C. Parolin; C. Cappadone; F. Di Giorgio; J. Hysomema; M.L. Bolognesi; C. Melchiorre; L. Masotti, CYTOTOXICITY EVALUATION OF A POLYAMINE-QUINONE LIBRARY CONJUGATES IN HUMAN COLON CARCINOMA CELLS, in: 53° National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB), proceedings and report, FIRENZE, Firenze, university press, 2008, pp. 2.42 - 2.42 (atti di: 53° National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB), Riccione, Italy, 23-26 settembre 2008) [atti di convegno-abstract]

M.L. Bolognesi; P. Carloni; G. Legname, Design and synthesis of a library of benzoquinone derivatives as probes to modulate protein-protein interactions in prions, in: International Workshop HUMAN and ANIMAL TSE, Programme Abstracts, s.l, s.n, 2008, pp. 30 - 30 (atti di: International Workshop Human and Animal TSE, Grado, Italy, 26-28 June 2008) [atti di convegno-abstract]

M. L. Bolognesi; A. Cavalli, Design and synthesis of new classes of derivatives bearing antitrypanosomal and antileishmanial activity, in: XIII Meeting Strutture Eterocicliche nella Ricerca Farmaceutica, Atti, S. L., s. n., 2008, pp. 170 - 180 (atti di: XIII Meeting Strutture Eterocicliche nella Ricerca Farmaceutica, Palermo, 18-21 maggio 2008) [Contributo in Atti di convegno]

A. Kranjc; S. Bongarzone; G. Chiriano; G. Rossetti; X. Biarnés; A. Cavalli; M.L. Bolognesi; M. Roberti; G. Legname; P. Carloni, DESIGN OF LIGANDS WITH A HIGH AFFINITY TO PrPC, in: International Workshop HUMAN and ANIMAL TSE, Programme Abstracts, S. L., s. n., 2008, pp. 34 - 34 (atti di: International Workshop HUMAN and ANIMAL TSE, Grado, Italy, 26-28 Giugno 2008) [atti di convegno-abstract]

A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre, Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 7311 - 7320 [articolo]

M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre, From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease, «MINI-REVIEWS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 960 - 967 [articolo]

M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 4381 - 4384 [articolo]

A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre, Multi-target-Directed Ligands To Combat Neurodegenerative Diseases, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 347 - 372 [articolo]

Maria Laura Bolognesi; Federica Lizzi; Christian Bergamini; Serena Leone; Romana Fato; Andrea Cavalli, Parallel synthesis and biological evaluation of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing antitrypanosomal and antileishmanial activity, in: XII Meeting Strutture Eterocicliche nella Ricerca Farmaceutica, Atti, S. L., s. n., 2008, pp. 205 - 205 (atti di: XII Meeting Strutture Eterocicliche nella Ricerca Farmaceutica,, Palermo, 18-21 maggio 2008) [atti di convegno-abstract]

Bolognesi ML; Calonghi N; Mangano C; Masotti L; Melchiorre C., Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 5463 - 5467 [articolo]

V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre, Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2008, 18, pp. 387 - 401 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre, Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7308 - 7312 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone, in: Atti del XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 207 - 207 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]