Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHEM-07/A Chimica farmaceutica

Coordinatrice del Corso di Dottorato in Drug discovery and development

Pubblicazioni

Bolognesi ML; Calonghi N; Mangano C; Masotti L; Melchiorre C., Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 5463 - 5467 [articolo]

V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre, Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2008, 18, pp. 387 - 401 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre, Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7308 - 7312 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone, in: Atti del XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 207 - 207 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]

A. Cavalli; M. L. Bolognesi, Structure-based design and synthesis of inhibitors of the trypanothione reductase enzyme from Trypanosoma cruzi., in: XIX National Meeting on Medicinal Chemistry, Book of Abstracts, S. L., s. n., 2008, pp. 180 - 180 (atti di: XIX National Meeting on Medicinal Chemistry, Verona, 14-18 Settembre 2008) [atti di convegno-abstract]

Bolognesi ML; Lizzi F; Perozzo R; Brun R; Cavalli A., Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2008, 18, pp. 2272 - 2276 [articolo]

ML. Bolognesi; A. Minarini; M. Bartolini; A. Cavalli; F. Mancini; V. Andrisano; M. Rosini; V. Tumiatti; C. Melchiorre, Synthesis of monomeric derivatives to probe Memoquin bivalent interactions, in: Book of Abstracts, s.l, s.n, 2008, pp. 226 - 226 (atti di: XIX National Meeting on Medicinal Chemistry, Verona, 14-18 September 2008) [atti di convegno-abstract]

A. Cavalli; Ml.L. Bolognesi, Two medicinal chemistry approaches to the search for new antitrypanosomal and antileishmanial agents, in: Book of proceedings of the International Conference on Drug Design and Discovery for Developing Countries, TRIESTE, ICS-UNIDO, 2008, pp. XX - YY (atti di: International Conference on Drug Design and Discovery for Developing Countries, Trieste, 3-5 July 2008) [Contributo in Atti di convegno]

Calonghi N; Pagnotta E; Parolin C; Mangano C; Bolognesi ML; Melchiorre C; Masotti L., A new EGFR inhibitor induces apoptosis in colon cancer cells., «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2007, 354, pp. 409 - 413 [articolo]

Cavalli A.; Bolognesi M. L.; Capsoni S.; Andrisano V.; Bartolini M.; Margotti E.; Cattaneo A.; Recanatini M.; Melchiorre C., A small molecule targeting the multifactorial nature of Alzheimer's disease, «ANGEWANDTE CHEMIE. INTERNATIONAL EDITION», 2007, 46, pp. 3689 - 3692 [articolo]

Mancini F.; Bolognesi ML.; Minarini A.; Melchiorre C.; Andrisano V., Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors., in: Frontiers in CNS and oncology medicinal chemistry-program and abstracts, s.l, s.n, 2007, pp. 51 - 52 (atti di: Frontiers in CNS and oncology medicinal chemistry, Siena (Italy), 7-9 October, 2007) [atti di convegno-abstract]

M. Bartolini; M.L. Bolognesi; A. Cavalli; C. Melchiorre; A. Rampa; M. Recanatini; V. Andrisano, Characterization of Cholinesterase inhibitors by means of immobilized enzyme reactor, in: The IXth International Meeting on Cholinesterases, Program Book, s.l, s.n, 2007, pp. 69 - 69 (atti di: IXth International Meeting on Cholinesterases, Suzhou, China, 6-10 Maggio 2007) [Contributo in Atti di convegno]

Piccoli A.; Nordström H.; Bertucci C.; Bolognesi M.; Danielson H.U., IN VITRO PROTEIN BINDING STUDY BETWEEN ANTITUMOR DRUGS AND DIFFERENT ALBUMINS: A SURVAY AMONG SPECIES DIFFERENCES, in: 12th International Meeting on Recent Developments in Pharmaceutical Analysis RDPA 2007, s.l, s.n, 2007, pp. 67 - 67 (atti di: 12th International Meeting on Recent Developments in Pharmaceutical Analysis RDPA 2007, Island of Elba, Italy, September 23-26, 2007) [atti di convegno-abstract]

M. Bartolini; C. Bertucci; M.L. Bolognesi; A. Cavalli; C. Melchiorre; V. Andrisano, Insight Into the Kinetic of Amyloid beta (1-42) Peptide Self-Aggregation: Elucidation of Inhibitors' Mechanism of Action, «CHEMBIOCHEM», 2007, 8, pp. 2152 - 2161 [articolo]

Bolognesi ML; Cavalli A; Andrisano V; Bartolini M; Minarini A; Melchiorre C, Memoquine derivatives as potent inhibitors of AChE-induced amyloid-beta aggregation, in: Programme and abtracts 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry, s.l, s.n, 2007, pp. 117 - 117 (atti di: 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry, Camerino, September 9-13, 2007) [Contributo in Atti di convegno]