Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Coordinatrice del Corso di Dottorato in Scienze biotecnologiche, biocomputazionali, farmaceutiche e farmacologiche

Pubblicazioni

Minarini A.; Milelli A.; Tumiatti V.; Rosini M.; Bolognesi M.L.; Melchiorre C., Synthetic polyamines: an overview of their multiple biological activities., «AMINO ACIDS», 2010, 38, pp. 383 - 392 [articolo]

Tumiatti V.; Minarini A.; Bolognesi M.L.; Milelli A.; Rosini M.; Melchiorre C., Tacrine Derivatives and Alzheimer's Disease, «CURRENT MEDICINAL CHEMISTRY», 2010, 17, pp. 1825 - 1838 [articolo]

Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C., Alzheimer's disease: new approaches to drug discovery., «CURRENT OPINION IN CHEMICAL BIOLOGY», 2009, 13, pp. 303 - 308 [articolo]

Kranjc A.; Bongarzone S.; Rossetti G.; Biarnes X.; Cavalli A.; Bolognesi M. L.; Roberti M.; Legname G.; Carloni P., Docking ligands on protein surfaces: the case study of prion protein., «JOURNAL OF CHEMICAL THEORY AND COMPUTATION», 2009, 5, pp. 2565 - 2573 [articolo]

Mancini F.; Bolognesi M.L.; Melchiorre C.; Andrisano V., Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease., «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2009, 50(2), pp. 164 - 170 [articolo]

Bolognesi ML; Cavalli A; Melchiorre C., Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease, «NEUROTHERAPEUTICS», 2009, 6, pp. 152 - 162 [articolo]

Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C., MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond, «CURRENT PHARMACEUTICAL DESIGN», 2009, 15, pp. 601 - 613 [articolo]

M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease, in: , «DRUGS OF THE FUTURE», 2009, 34, pp. 195 - 195 (atti di: Frontiers in medicinal chemistry: Emerging targets, novel candidates and innovative strategies, Barcelona, October, 4-6, 2009) [atti di convegno-abstract]

M. L. Bolognesi, Multi-target-directed ligands as an innovative therapeutic opportunity for Alzheimer's disease, in: Meeting Program-Abstract Book, s.l, s.n, 2009, pp. 42 - 43 (atti di: 6th International Winter Conference on Alzheimer's Disease: “Why do we have so few Drugs for Treatment of Alzheimer’s Disease –wrong Patients, wrong Targets, wrong Drugs?“ A critical discussion, Zuers, Austria, Saturday, 5th of December to Tuesday, 8th of December 2009) [Contributo in Atti di convegno]

Cavalli A; Bolognesi ML, Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 7339 - 7359 [articolo]

Brevetto n. WO 2009034457, Organic compounds useful for the treatment of neurodegenerative diseases, uses and methods for the preparation thereof.

A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre, Polymethylene tetraamine backbone as template for the development of biologically active polyamines, in: Biogenic amines: biochemical, physiological and clinical aspects, s.l, s.n, 2009, pp. 14 - 14 (atti di: Biogenic amines: biochemical, physiological and clinical aspects, Bertinoro (FC, Italy), 11-14, 2009) [atti di convegno-abstract]

Brevetto n. US 7,589,219 B2, Preparation of 2,5-bis-diamine-[1,4]benzoquinone derivatives for the treatment of Alzheimer's disease and a process for their preparation and intermediates thereof..

Cavalli A; Lizzi F; Bongarzone S; Brun R; Luise Krauth-Siegel R; Bolognesi ML, Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2009, 19, pp. 3031 - 3035 [articolo]

Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C., Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2009, 19, pp. 4312 - 4315 [articolo]