Perez-Areales F.J.; Turcu A.L.; Barniol-Xicota M.; Pont C.; Pivetta D.; Espargaro A.; Bartolini M.; De Simone A.; Andrisano V.; Perez B.; Sabate R.; Sureda F.X.; Vazquez S.; Munoz-Torrero D., A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 180, pp. 613 - 626 [articolo]
Hulcova D.; Marikova J.; Korabecny J.; Hostalkova A.; Jun D.; Kunes J.; Chlebek J.; Opletal L.; De Simone A.; Novakova L.; Andrisano V.; Ruzicka A.; Cahlikova L., Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease, «PHYTOCHEMISTRY», 2019, 165, Article number: 112055, pp. 112055 - 112063 [articolo]
De Simone A.; La Pietra V.; Betari N.; Petragnani N.; Conte M.; Daniele S.; Pietrobono D.; Martini C.; Petralla S.; Casadei R.; Davani L.; Frabetti F.; Russomanno P.; Novellino E.; Montanari S.; Tumiatti V.; Ballerini P.; Sarno F.; Nebbioso A.; Altucci L.; Monti B.; Andrisano V.; Milelli A., Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507), «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 1357 - 1357 [articolo]
De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A., Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease., «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 469 - 474 [articolo]Open Access
De Simone, Angela*; Naldi, Marina; Bartolini, Manuela; Davani, Lara; Andrisano, Vincenza, Immobilized Enzyme Reactors: an Overview of Applications in Drug Discovery from 2008 to 2018, «CHROMATOGRAPHIA», 2019, 82, pp. 425 - 441 [articolo]
De Simone A.; Naldi M.; Tedesco D.; Milelli A.; Bartolini M.; Davani L.; Widera D.; Dallas M.L.; Andrisano V., Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts, «ACS OMEGA», 2019, 4, pp. 12308 - 12318 [articolo]Open Access
Hostalkova A.; Marikova J.; Opletal L.; Korabecny J.; Hulcova D.; Kunes J.; Novakova L.; Perez D.I.; Jun D.; Kucera T.; Andrisano V.; Siatka T.; Cahlikova L., Isoquinoline alkaloids from berberis vulgaris as potential lead compounds for the treatment of alzheimer's disease, «JOURNAL OF NATURAL PRODUCTS», 2019, 82, pp. 239 - 248 [articolo]
Heider F.; Pantsar T.; Kudolo M.; Ansideri F.; De Simone A.; Pruccoli L.; Schneider T.; Goettert M.I.; Tarozzi A.; Andrisano V.; Laufer S.A.; Koch P., Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks, «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 1407 - 1414 [articolo]
de simone a, naldi m, tedesco d, bartolini m, andrisano v, A multi-methodological approach for the investigation of β-Amyloid-CORMs interaction: an LC-ESI/MS and Circular Dichroism study., in: 10° MS pharma day book of abstracts, 2018, pp. 15 - 16 (atti di: 10° MS pharma day, Colleretto Giacosa (TO), 24-26 Ottobre) [Contributo in Atti di convegno]
Andrisano, Vincenza*; Naldi, Marina; De Simone, Angela; Bartolini, Manuela, A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2018, 28, pp. 455 - 465 [articolo]
A De Simone; M Naldi; D Tedesco; M Bartolini; V Andrisano, β-Amyloid-CORMs interaction monitoring by LC-ESI/MS and Circular Dichroism studies, in: Med Chem Sicily 2018, 2018, pp. 18 - 18 (atti di: Med Chem Sicily 2018, Palermo, 17-20 July 2018) [Contributo in Atti di convegno]
Angela De Simone, Marina Naldi, Daniele Tedesco, Manuela Bartolini, Vincenza Andrisano, Integrated analytical methodologies for Alzheimer's disease drug discovery, in: DA-PBA 2018 book of abstracts, 2018, pp. 148 - 148 (atti di: DA-PBA 2018, Leuven, Belgio, 9-12 Settembre 2018) [Contributo in Atti di convegno]
m BARTOLINI, a DE SIMONE, V ANDRISANO, Synthesis and pharmacological evaluation of a novel class of multi target Huprine-based anti-Alzheimer hybrids, in: Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry MedChemSicily 2018 book of abstracts, 2018, pp. 13 - 13 (atti di: Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry MedChemSicily 2018, palermo, 17-20 July 2018) [Contributo in Atti di convegno]
De Simone, Angela; Fiori, Jessica; Naldi, Marina; D'Urzo, Annalisa; Tumiatti, Vincenzo; Milelli, Andrea; Andrisano, Vincenza, Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2017, 144, pp. 159 - 166 [articolo]
Pérez-Areales, Francisco Javier; Betari, Nibal; Viayna, Antonio; Pont, Caterina; Espargarã³, Alba; Bartolini, Manuela; DE SIMONE, Angela; Rinaldi Alvarenga, José Fernando; Pã©rez, Belã©n; Sabate, Raimon; Lamuela-Raventós, Rosa Maria; Andrisano, Vincenza; Luque, Francisco Javier; Muñoz-Torrero, Diego, Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids, «FUTURE MEDICINAL CHEMISTRY», 2017, 9, pp. 965 - 981 [articolo]
