Foto del docente

Sofia Asioli

Associate Professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: MED/08 Pathology


Keywords: Next generation Sequensing merkel cell carcinoma breast Neuroendocrine Tumor Head and Neck RNA Ibridizazione in situ DNA Thyroid microRNA Neuropathology

Research Activities:

Scientific Research in the field of Experimental and Clinico-Pathological studies on head and neck, neuroendocrine, thyroid, lung , breast and gastro-intestinal tumor.


 Full knowledge and use of diagnostic morphological techniques (such as fluorescence in situ hybridization and immunohistochemistry) and molecular (comparative genomic hybridization analysis of clonality by analysis of the D-loop region of mitochondrial DNA and the study of micro-RNA, Next Generation Sequensing analysis), in 'field research and diagnostics in surgical pathology and cytopathology.


Relevant Research results:

·         the PI has identified a new aggressive variant of thyroid carcinoma so called the Hobnail papillary thyroid carcinoma as (see reference 17, Asioli S et al Am J Surg Pathol 2010).

·         the PI showed an extension of the phenotypes associated with mutations in DICER1 including Head and Neck diseases ( see reference Foulkes WD et al. Hum Mutat. 2011) in collaboration with the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Clinical trials:  HER-EAGLE (MO23009) faunded by  Roche. Dr. Giovanni Castegnaro, Clinical Research Associate,  MediData srl - Studi e Ricerche c/o Centro servizi Città Nova, Viale Virgilio 56/A,  41123 Modena, Italy Tel: +39 059 88.60.134, Fax: +39 059 84.83.05. Recruitment of  patients with HER2 positive advanced gastric adenocarcinoma closed in February 2012.



·         Research Collaborator of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

·         Research Collaborator of University of Madison, Wisconsin, USA.

·         Research Colaborator of the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Research Colaborator of the, Department of Medicine, University of Washington, Seattle, Washington 98109, USA.


Grant Proposals  (Total =12 grants):

·         Head of research 8 projects funded by the University of Turin (ex-finance 60% MIUR, 5 projects 2008, 2009, 2010, 2011, 2012, 2013) and by Regione Piemonte (Piedmont Healthcare Research aimed Region, 3 projects 2007, 2008, 2008-bis and 1 project of CRT foundation 2008) See Websites: and


Paired Related Homeobox 1 (PRRX1) Is Associated with Epithelial-Mesenchymal Transition (EMT) in Thyroid Tumors . Garcia CM, Guo Z, Hardin H, Buehler D, Nose V, Asioli S,  et al. was selected in the Stowell-Orbison/Surgical Pathology/Autopsy Awards Poster Session at United States & Canadian Academy of Pathology (USCAP) Annual Meeting 2014, San Diego, CA, USA; Modern Pathology 2014 Feb.

Organisational skills :

·         Member of Endocrine Society of Pathology

·         Member of Endocrine Tumor Team of Romagna (NetteR)

·         Member of Merkel cell carcinoma Multi-center Interest Group

·         Member of Adriatic Society of Pathology.

·         Member of SIAPEC-IAP (Italian Society of Pathological Anatomy & Citology – Italian division of International Academy of Pathology) sub-group of Head and Neck pathology.


Author of 71 publications, since 2002, on "peer review journals", 4 book chapter,  and  44 abstracts  published on

peer review journals.


The current bibliometric data are

Articles published in journals with impact factor: 71/71

Impact Factor of the total journal papers:206,428

Impact Factor for the average article in a journal:3.88

Number of citations:  1145 (Scopus), 912 (ISI Web of Science), 1543 (Google Scholar) h-index:20 (Scopus) 18 (ISI Web of Science), 23 (Google Scholar).



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