CURRICULUM VITAE
Sofia Asioli
Address: Via Murri n. 120 ; 40100 Bologna, Italy
Phone: +39 051 6225006
Mobile:+39 347 8296311
Mail : sofia.asioli3@unibo.it
Date of birth: 13/04/1976
Occupational field: University, Health
Education and training:
2001: University of Bologna
2006: Professional specialist, Faculty of Medicine, University
of Turin
Title of qualification awarded:
2001: Graduated at Medical School, Magna cum laude
2006: Degree as a MD specialized in Pathological Anatomy and
Histology, University of Turin, Italy
2011: Master II level Dermatopathology , University of Turin,
Italy.
Fellowships:
2003 Surgical Pathology, Istituto Nazionale dei Tumori, Milano,
Italy ( Juan Rosai, MD.)
2004 Breast Pathology ,Università degli Studi di Bologna, Italy
(Vincenzo Eusebi, MD, FRC)
2005 Hematopathology, Istituto di Ematologia e Clinica
Oncologica 'L. and A. Seràgnoli', Università degli Studi di
Bologna, Italy, (Stefano Aldo Pileri, MD.)
2/28/2009-8/28/09: Visiting Clinician Mayo Clinic, Rochester,
Minnesota. Surgical Pathologist Lab. Ricardo Lloyd, MD, PhD
Work experience:
2013-present
Occupation or position held:
Assistant Professor, Associate Medical Doctor ,
University of Bologna, Italy.
Main activities and responsibilities:
University and post-University teaching activity. Assistant
Professor, Pathological Anatomy and Histology, Department of
Biomedical and Neuromotor Sciences (DIBINEM)-Surgical Pathology
Section- Alma Mater Studiorum - University of Bologna
Scientific Research in the field of Experimental and
Clinico-Pathological studies on head and neck, neuroendocrine,
thyroid, lung , breast and gastro-intestinal tumor.
Co-responsibility of the Pathological Anatomy and Histology
Unit, San Giovanni Hospital Turin for head and neck and
neuroendocrine pathology.
Name and address of employer:
Full Professor Maria Pia Foschini, Department of Biomedical and
Neuromotor Sciences (DIBINEM)-Surgical Pathology Section- Alma
Mater Studiorum - University of Bologna
(mariapia.foschini@unibo.it).
Type of business or sector:
Education, Health
2005-2013
Occupation or position held:
Assistant Professor, Associate Medical Doctor ,
University of Torino, Italy.
Main activities and responsibilities:
University and post-University teaching activity.
Assistant Professor,, Pathological Anatomy and Histology,
Dept. of Biomedical Sciences & Human Oncology, University of
Turin.
Scientific Research in the field of Experimental and
Clinico-Pathological studies on endocrine, neuroendocrine, thyroid,
lung , pancreas and gastro-intestinal tumor.
Responsibility of the Pathological Anatomy and Histology Unit,
San Giovanni Hospital Turin for endocrine and
neuroendocrine pathology.
Name and address of employer:
Full Professor Anan Sapino, Dept. of Biomedical Sciences &
Human Oncology, University of Turin San Giovanni Hospital, Turin
(anna.sapino@unito.it)
Type of business or sector:
Education, Health
Educational Activity
2005-2013: Assistant Professor of Pathology Anatomy and
Histology of University of Turin
2005-2013: Trainer and Tutor for Resident School Of Anatomic
Pathology, University of Turin
2005-2013: Assistant Professor of Cytopathology for Master
of II level in cytology, Univeristy of Turin.
2007-2013: Assistant Professor and coordinator of
Pathology Anatomy and Histology, in School for Cytotechnologists of
the University of Cuneo.
2007-2013: Trainer and Tutor for Resident School Of
General Pathology, University of Turin
2007-2013: Assistant Professor of Gastrointestinal
pathology for Master of II level in gastroenterology,
Univeristy of Turin.
2007-2013: Assistant Professor of Lung pathology for
Master of II level in thoracic surgery, Univeristy of Turin.
12.12.2013-present: Assistant Professor for Corso di Laurea in
Odontoiatria e Protesi Dentaria, university of Bologna.
12.12.2013-present: Trainer and Tutor for Resident School Of
Anatomic Pathology, University of Bologna
12.12.2013-present: Trainer and Tutor for Anatomic Pathology,
University of Bologna.
Organisational skills and competences:
· Full knowledge
and use of diagnostic morphological techniques (such as
fluorescence in situ hybridization and immunohistochemistry) and
molecular (comparative genomic hybridization analysis of clonality
by analysis of the D-loop region of mitochondrial DNA and the study
of micro-RNA, Next Generation Sequensing analysis), in 'field
research and diagnostics in surgical pathology and
cytopathology.
· Member of
Endocrine Society of Pathology
· Member of
Endocrine Tumor Team of Romagna (NetteR)
· Member of
Merkel cell carcinoma Multi-center Interest Group
· Member of
Adriatic Society of Pathology.
· Member of
SIAPEC-IAP (Italian Society of Pathological Anatomy & Citology
– Italian division of International Academy of Pathology) sub-group
of Head and Neck pathology.
Awards
Paired Related Homeobox 1 (PRRX1) Is Associated with
Epithelial-Mesenchymal Transition (EMT) in Thyroid Tumors . Garcia
CM, Guo Z, Hardin H, Buehler D, Nose V, Asioli S, et
al. was selected in the Stowell-Orbison/Surgical
Pathology/Autopsy Awards Poster Session at United States &
Canadian Academy of Pathology (USCAP) Annual Meeting 2014, San
Diego, CA, USA; Modern Pathology 2014 Feb.
Collaborations:
· Research
Collaborator of Laboratory Medicine and Pathology, Mayo Clinic,
Rochester, MN, USA
· Research
Collaborator of University of Madison, Wisconsin, USA.
· Research
Colaborator of the Research Institute, McGill University Health
Centre, Montreal, Quebec, Canada.
· Research
Colaborator of the, Department of Medicine, University of
Washington, Seattle, Washington 98109, USA.
Relevant Research Activities:
· the PI has
identified a new aggressive variant of thyroid carcinoma so called
the Hobnail papillary thyroid carcinoma as (see reference 17,
Asioli S et al Am J Surg Pathol 2010).
· the PI showed
an extension of the phenotypes associated with mutations in DICER1
including Head and Neck diseases ( see reference Foulkes WD et al.
Hum Mutat. 2011) in collaboration with the Research Institute,
McGill University Health Centre, Montreal, Quebec, Canada.
· Clinical
trials: HER-EAGLE (MO23009) faunded by Roche. Dr.
Giovanni Castegnaro, Clinical Research Associate, MediData
srl - Studi e Ricerche www.medidata.it c/o Centro servizi Città
Nova, Viale Virgilio 56/A, 41123 Modena, Italy Tel: +39 059
88.60.134, Fax: +39 059 84.83.05. Recruitment of patients
with HER2 positive advanced gastric adenocarcinoma closed in
February 2012.
Grant Proposals (Total =12 grants):
· Head of
research 8 projects funded by the University of Turin (ex-finance
60% MIUR, 5 projects 2008, 2009, 2010, 2011, 2012, 2013) and
by Regione Piemonte (Piedmont Healthcare Research aimed Region,
3 projects 2007, 2008, 2008-bis and 1 project of CRT
foundation 2008) See Websites: www.sitouniversitario.cineca.it and
http://www.ricerca-sanitaria-finalizzata.it.
1. Responsible of the
project funded by MIUR,University of Torino (MIUR
Università di Torino (ex-60%) 2007): NEO-ANGIOGENESIS AND
TRANSGLUTAMINASE 2 EXPRESSION IN PERI-IMPLANT SOFT TISSUES:
PRELIMINARY EVIDENCE OF A RELATION WITH IMPLANT FAILURE THROUGH AN
AUTOMATED HISTOLOGICAL APPROACH USING DIGITAL VIRTUAL MICROSCOPY
(software Amira 4.0; TGS Template Graphics Software
(http://www.tgs.com)
2. Responsible of the
project funded by Ricerca Sanitaria Finalizzata-Regione Piemonte
2007: CARCINOMA POCO DIFFERENZIATO DELLA TIROIDE: NUOVI INDICATORI
DELLA APPROPRIATEZZA E SOBRIETA' DELLA CURA in collaboration
with Prof. Gianni Bussolati MD FRC Path, Dipartimento di
Scienze Biomediche e Oncologia Umana, Università di Torino,
Italia.
3. Responsible of the
project funded by Fondazione CRT 2008” CORSO DI AGGIORNAMENTO
IN ISTOPATOLOGIA SULLA PATOLOGIA ENDOCRINA: CLASSIFICAZIONE
DELL'ORGANIZZAZIONE MONDIALE DELA SANITA' E NUOVI MARKERS NEI
TUMORI ENDOCRINI in collaboration with Prof. Gianni Bussolati
MD FRC Path, Dipartimento di Scienze Biomediche e Oncologia Umana,
Università di Torino, Italia.
4. Responsible of the
project funded by MIUR University of Torino (MIUR
Università di Torino (ex-60%) 2008: SIGNIFICATO DELL'AMPLIFICAZIONE
E DELL' IPERESPRESSIONE DI p63 NEL CARCINOMA A CELLULE DI MERKEL
DELLA CUTE, in collaboration with Prof. Mario Pippione MD,
Department of Dermatopathology, University of Turin, Italy and with
Prof. Paul Nighiem, Department of Medicine, University of
Washington, Seattle, Washington 98109, USA.
5. Responsible of the
project funded by Ricerca Sanitaria finalizzata Regione
Piemonte Anno 2008: PREDITTIVITÀ PROGNOSTICO-TERAPEUTICA
DELL'ESPRESSIONE DELLA P63 NEL CARCINOMA A CELLULE DI MERKEL,
in collaboration with Prof. Mario Pippione MD, Department of
Dermatopathology, University of Turin, Italy and with Prof. Paul
Nighiem, Department of Medicine, University of Washington, Seattle,
Washington 98109, USA.
6. Responsible of the
project funded by Ricerca Sanitaria finalizzata Regione
Piemonte- Bando per il finanziamento di Progetti di ricerca
sanitaria finalizzata Anno 2008 – BIS: PREDITTIVITÀ
DIAGNOSTICA E PROGNOSTICO-TERAPEUTICA DELLO STATUS GENOMICO
NEL MELANOMA MALIGNO DELLA CUTE, in collaboration with
Prof. Mario Pippione MD, Department of Dermatopathology, University
of Turin, Italy and with Prof. ssa Anna Sapino, Dipartimento di
Scienze Biomediche e Oncologia Umana, Università di Torino, Italia
.
7. Responsible of the
project World Wide Style (WWS) 2008-2009 funded by University
of Turin “INNOVATIVE DIAGNOSTIC APPROACH AND MOLECULAR
DEFINITION OF POORLY DIFFERENTIATED THYROID CARCINOMAS”, in
collaboration with Prof. Ricardo V. Lloyd, Departments
Laboratory Medicine and Pathology, MAYO Clinic, Minnesota -
Rochester USA. The PI has carried out the WWS research at the
Mayo Clinic Visiting Clinician Program in 2009.
8. Responsible of the
project ex-60% MIUR funded by University of Turin (MIUR
Università di Torino (ex-60%) anno: 2009-2010.
9. Responsible of the
project ex-60% MIUR funded by University of Turin (MIUR
Università di Torino (ex-60%) anno: : 2011-2012.
· Co-worker to 3
research projects funded by the Italian Association of Cancer
Research (AIRC, 3 projects 2004, 2005, 2007), See website: www.airc.it,
a. Grant Proposal AIRC 2004
GENETIC RELATIONSHIP AMONG ATYPICAL ADENOMATOUS
HYPERPLASIA, BRONCHIOLOALVEOLAR CARCINOMA AND ADENOCARCINOMA OF
THE LUNG in collaboration with Stefania Damiani, Sezione di
Anatomia Patologica, Ospedale “M. Malpighi”, Università di Bologna,
Ospedale Bellaria, Bologna, Italia.
b. Grant Proposal AIRC 2005:
GENETIC AND FUNCTIONAL CHARACTERIZATION OF LOBULAR CARCINOMA OF THE
BREAST FOR CLINICAL MANAGEMENT in collaboration with Prof.
Vincenzo Eusebi MD FRC Path, Sezione di Anatomia Patologica,
Ospedale “M. Malpighi”, Università di Bologna, Ospedale
Bellaria, Bologna, Italia.
c. Grant Proposal AIRC
2007: INNOVATIVE DIAGNOSTIC APPROACH AND MOLECULAR DEFINITION OF
POORLY DIFFERENTIATED THYROID CARCINOMAS in collaboration
with Prof. Gianni Bussolati MD FRC Path, Dipartimento di
Scienze Biomediche e Oncologia Umana, Università di Torino,
Italia.
Publications:
Author of 71publications, since 2002, on "peer review
journals",4 book chapterS, and 44 abstracts published on
peer review jOURNAL
The current bibliometric data
are:
h-index: 37 (Scopus)
BRIEF TRACK-RECORD OF SOFIA ASIOLI
· Research of
Surgical Pathology at the University of Bologna .
· Research
Collaborator of Laboratory Medicine and Pathology, Mayo Clinic,
Rochester, MN, USA
· Research
Collaborator of University of Madison, Wisconsin, USA.
· Research
Colaborator of the Research Institute, McGill University Health
Centre, Montreal, Quebec, Canada.
· Responsible
for the Head and Neck and Neuroendocrine Pathology Group at the
Department of Biomedical Science and Human Pathology at Turin
University until 31/10/2013
·
Co-responsible for the Head and Neck Pathology Group at the
Department of Department of Biomedical and Neuromotor
Sciences at Bologna University from 01/11/2013 to present
· Member of
the Endocrine Pathology Society and of the Head and Neck Italian
pathology group (SIAPEC-IAP).
Publications:
Author of 55 publications, since 2002, on "peer review
journals", 1 book chapter, and 41
abstracts published on
peer review journals.
The current bibliometric data are: Articles
published in journals with impact factor: 60/60; Impact Factor of the total journal papers:192,462Impact Factor for the average article in a journal:3.62Number of citations:746(Scopus), 698 (ISI Web of Science), 1041 (Google Scholar) h-index:16 (Scopus) 15 (ISI Web of Science), 19(Google Scholar).
Grant Proposals (Total =12 grants):
· Head of
research 8 projects funded by the University of Turin (ex-finance
60% MIUR, 5 projects 2008, 2009, 2010, 2011, 2012, 2013) and
by Regione Piemonte (Piedmont Healthcare Research aimed Region,
3 projects 2007, 2008, 2008-bis and 1 project of CRT
foundation 2008) See Websites: www.sitouniversitario.cineca.it and
http://www.ricerca-sanitaria-finalizzata.it.
· Co-worker to 3
research projects funded by the Italian Association of Cancer
Research (AIRC, 3 projects 2004, 2005, 2007), See website:
www.airc.it,
· the PI won
the World Wide Style (WWS) project of University of Turin 2009
entitled "innovative and molecular diagnostic approach definition
of thyroid poorly differentiated carcinomas," in collaboration with
Prof. Ricardo V. Lloyd, Laboratory Medicine and Pathology
Departments, MAYO Clinic, Rochester, MN, USA and she has carried
out the WWS research at the Mayo Clinic Visiting Clinician Program
in 2009.
Relevant Research Activities:
· the PI has
identified a new aggressive variant of thyroid carcinoma so called
the Hobnail papillary thyroid carcinoma as (see reference 17,
Asioli S et al Am J Surg Pathol 2010).
· the PI showed
an extension of the phenotypes associated with mutations in DICER1
including Head and Neck diseases ( see reference Foulkes WD et al.
Hum Mutat. 2011) in collaboration with the Research Institute,
McGill University Health Centre, Montreal, Quebec, Canada.
· Full knowledge
and use of diagnostic morphological techniques (such as
fluorescence in situ hybridization and immunohistochemistry) and
molecular (comparative genomic hybridization analysis of clonality
by analysis of the D-loop region of mitochondrial DNA and the study
of micro-RNA, Next Generation Sequensing analysis), in 'field
research and diagnostics in surgical pathology and
cytopathology.
Educational Activity
2005-2013: Assistant Professor of Pathology Anatomy and
Histology of University of Turin
2005-2013: Trainer and Tutor for Resident School Of Anatomic
Pathology, University of Turin
2005-2013: Assistant Professor of Cytopathology for Master
of II level in cytology, Univeristy of Turin.
2007-2013: Assistant Professor and coordinator of
Pathology Anatomy and Histology, in School for Cytotechnologists of
the University of Cuneo.
2007-2013: Trainer and Tutor for Resident School Of
General Pathology, University of Turin
2007-2013: Assistant Professor of Gastrointestinal
pathology for Master of II level in gastroenterology,
Univeristy of Turin.
2007-2013: Assistant Professor of Lung pathology for
Master of II level in thoracic surgery, Univeristy of Turin.
12.12.2013-present: Assistant Professor for Corso di Laurea in
Odontoiatria e Protesi Dentaria, university of Bologna.
12.12.2013-present: Trainer and Tutor for Resident School Of
Anatomic Pathology, University of Bologna
12.12.2013-present: Trainer and Tutor for Anatomic Pathology,
University of Bologna.
Awards
Paired Related Homeobox 1 (PRRX1) Is Associated with
Epithelial-Mesenchymal Transition (EMT) in Thyroid Tumors . Garcia
CM, Guo Z, Hardin H, Buehler D, Nose V, Asioli S, et
al. was selected in the Stowell-Orbison/Surgical
Pathology/Autopsy Awards Poster Session at United States &
Canadian Academy of Pathology (USCAP) Annual Meeting 2014, San
Diego, CA, USA; Modern Pathology 2014 Feb.
