Foto del docente

Sofia Asioli

Associate Professor

Department of Biomedical and Neuromotor Sciences

Academic discipline: MED/08 Pathology

Curriculum vitae

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CURRICULUM VITAE

Sofia Asioli

Address: Via Murri n. 120 ; 40100 Bologna, Italy

Phone: +39 051 6225006

Mobile:+39 347 8296311

Mail : sofia.asioli3@unibo.it

Date of birth: 13/04/1976

 

Occupational field: University, Health

 

Education and training: 

2001: University of Bologna

2006: Professional specialist, Faculty of Medicine, University of Turin

Title of qualification awarded:

2001: Graduated at Medical School, Magna cum laude

2006: Degree as a MD specialized in Pathological Anatomy and Histology, University of Turin, Italy

2011: Master II level Dermatopathology , University of Turin, Italy.

 

Fellowships:

2003 Surgical Pathology, Istituto Nazionale dei Tumori, Milano, Italy ( Juan Rosai, MD.)

2004 Breast Pathology ,Università degli Studi di Bologna, Italy (Vincenzo Eusebi, MD, FRC)

2005 Hematopathology, Istituto di Ematologia e Clinica Oncologica 'L. and A. Seràgnoli', Università degli Studi di Bologna, Italy,  (Stefano Aldo Pileri, MD.)

2/28/2009-8/28/09: Visiting Clinician Mayo Clinic, Rochester, Minnesota. Surgical Pathologist Lab. Ricardo Lloyd, MD, PhD

 

Work experience:

 

2013-present

Occupation or position held:

Assistant  Professor, Associate Medical  Doctor , University of Bologna, Italy.

Main activities and responsibilities:

University and post-University teaching activity. Assistant Professor, Pathological Anatomy and Histology, Department of Biomedical and Neuromotor Sciences (DIBINEM)-Surgical Pathology Section- Alma Mater Studiorum - University of Bologna

Scientific Research in the field of Experimental and Clinico-Pathological studies on head and neck, neuroendocrine, thyroid, lung , breast and gastro-intestinal tumor.

Co-responsibility of the Pathological Anatomy and Histology Unit, San Giovanni Hospital Turin  for  head and neck and neuroendocrine pathology.

Name and address of employer:

Full Professor Maria Pia Foschini, Department of Biomedical and Neuromotor Sciences (DIBINEM)-Surgical Pathology Section- Alma Mater Studiorum - University of Bologna (mariapia.foschini@unibo.it).

Type of business or sector:

Education, Health

 

2005-2013

Occupation or position held:

Assistant  Professor, Associate Medical  Doctor , University of Torino, Italy.

Main activities and responsibilities:

University and post-University teaching activity. Assistant  Professor,, Pathological Anatomy and Histology, Dept. of Biomedical Sciences & Human Oncology, University of Turin.

Scientific Research in the field of Experimental and Clinico-Pathological studies on endocrine, neuroendocrine, thyroid, lung , pancreas and gastro-intestinal tumor.

Responsibility of the Pathological Anatomy and Histology Unit, San Giovanni Hospital Turin  for  endocrine and neuroendocrine pathology.

Name and address of employer:

Full Professor Anan Sapino, Dept. of Biomedical Sciences & Human Oncology, University of Turin San Giovanni Hospital, Turin (anna.sapino@unito.it)

Type of business or sector:

Education, Health

 

Educational Activity

2005-2013: Assistant Professor of Pathology Anatomy and Histology of University of Turin

2005-2013: Trainer and Tutor for Resident School Of Anatomic Pathology, University of Turin

2005-2013: Assistant Professor of  Cytopathology for Master of II level in cytology, Univeristy of Turin.

2007-2013: Assistant Professor and coordinator  of  Pathology Anatomy and Histology, in School for Cytotechnologists of the University of Cuneo.

2007-2013: Trainer and Tutor for Resident School Of  General Pathology, University of Turin

2007-2013: Assistant Professor of Gastrointestinal pathology  for Master of II level in gastroenterology, Univeristy of Turin.

2007-2013: Assistant Professor of Lung pathology  for Master of II level in thoracic surgery, Univeristy of Turin.

12.12.2013-present: Assistant Professor for Corso di Laurea in Odontoiatria e Protesi Dentaria, university of Bologna.

12.12.2013-present: Trainer and Tutor for Resident School Of Anatomic Pathology, University of Bologna

12.12.2013-present: Trainer and Tutor for Anatomic Pathology, University of Bologna.

 

Organisational skills and competences:

·         Full knowledge and use of diagnostic morphological techniques (such as fluorescence in situ hybridization and immunohistochemistry) and molecular (comparative genomic hybridization analysis of clonality by analysis of the D-loop region of mitochondrial DNA and the study of micro-RNA, Next Generation Sequensing analysis), in 'field research and diagnostics in surgical pathology and cytopathology.

·         Member of Endocrine Society of Pathology

·         Member of Endocrine Tumor Team of Romagna (NetteR)

·         Member of Merkel cell carcinoma Multi-center Interest Group

·         Member of Adriatic Society of Pathology.

·         Member of SIAPEC-IAP (Italian Society of Pathological Anatomy & Citology – Italian division of International Academy of Pathology) sub-group of Head and Neck pathology.

Awards

Paired Related Homeobox 1 (PRRX1) Is Associated with Epithelial-Mesenchymal Transition (EMT) in Thyroid Tumors . Garcia CM, Guo Z, Hardin H, Buehler D, Nose V, Asioli S,  et al. was selected in the Stowell-Orbison/Surgical Pathology/Autopsy Awards Poster Session at United States & Canadian Academy of Pathology (USCAP) Annual Meeting 2014, San Diego, CA, USA; Modern Pathology 2014 Feb.

 

Collaborations:

·         Research Collaborator of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

·         Research Collaborator of University of Madison, Wisconsin, USA.

·         Research Colaborator of the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Research Colaborator of the, Department of Medicine, University of Washington, Seattle, Washington 98109, USA.

 

Relevant Research Activities:

·         the PI has identified a new aggressive variant of thyroid carcinoma so called the Hobnail papillary thyroid carcinoma as (see reference 17, Asioli S et al Am J Surg Pathol 2010).

·         the PI showed an extension of the phenotypes associated with mutations in DICER1 including Head and Neck diseases ( see reference Foulkes WD et al. Hum Mutat. 2011) in collaboration with the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Clinical trials:  HER-EAGLE (MO23009) faunded by  Roche. Dr. Giovanni Castegnaro, Clinical Research Associate,  MediData srl - Studi e Ricerche www.medidata.it c/o Centro servizi Città Nova, Viale Virgilio 56/A,  41123 Modena, Italy Tel: +39 059 88.60.134, Fax: +39 059 84.83.05. Recruitment of  patients with HER2 positive advanced gastric adenocarcinoma closed in February 2012.

 

Grant Proposals  (Total =12 grants):

·         Head of research 8 projects funded by the University of Turin (ex-finance 60% MIUR, 5 projects 2008, 2009, 2010, 2011, 2012, 2013) and by Regione Piemonte (Piedmont Healthcare Research aimed Region, 3 projects 2007, 2008, 2008-bis and 1 project of CRT foundation 2008) See Websites: www.sitouniversitario.cineca.it and http://www.ricerca-sanitaria-finalizzata.it.

 

1.       Responsible of the project funded  by MIUR,University of  Torino (MIUR Università di Torino (ex-60%) 2007): NEO-ANGIOGENESIS AND TRANSGLUTAMINASE 2 EXPRESSION IN PERI-IMPLANT SOFT TISSUES: PRELIMINARY EVIDENCE OF A RELATION WITH IMPLANT FAILURE THROUGH AN AUTOMATED HISTOLOGICAL APPROACH USING DIGITAL VIRTUAL MICROSCOPY (software Amira 4.0; TGS Template Graphics Software  (http://www.tgs.com)

2.       Responsible of the project funded by Ricerca Sanitaria Finalizzata-Regione Piemonte 2007: CARCINOMA POCO DIFFERENZIATO DELLA TIROIDE: NUOVI INDICATORI DELLA APPROPRIATEZZA E SOBRIETA' DELLA CURA in collaboration with  Prof. Gianni Bussolati MD FRC Path, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italia.

 

3.       Responsible of the project funded  by Fondazione CRT 2008” CORSO DI AGGIORNAMENTO IN ISTOPATOLOGIA SULLA PATOLOGIA ENDOCRINA: CLASSIFICAZIONE DELL'ORGANIZZAZIONE MONDIALE DELA SANITA' E NUOVI MARKERS NEI TUMORI ENDOCRINI in collaboration with  Prof. Gianni Bussolati MD FRC Path, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italia.

 

4.       Responsible of the project funded  by MIUR University of  Torino (MIUR Università di Torino (ex-60%) 2008: SIGNIFICATO DELL'AMPLIFICAZIONE E DELL' IPERESPRESSIONE DI p63 NEL CARCINOMA A CELLULE DI MERKEL DELLA CUTE, in collaboration with  Prof. Mario Pippione MD, Department of Dermatopathology, University of Turin, Italy and with Prof. Paul Nighiem, Department of Medicine, University of Washington, Seattle, Washington 98109, USA.

 

5.       Responsible of the project funded  by Ricerca Sanitaria finalizzata Regione  Piemonte Anno 2008: PREDITTIVITÀ PROGNOSTICO-TERAPEUTICA DELL'ESPRESSIONE DELLA  P63 NEL CARCINOMA A CELLULE DI MERKEL, in collaboration with  Prof. Mario Pippione MD, Department of Dermatopathology, University of Turin, Italy and with Prof. Paul Nighiem, Department of Medicine, University of Washington, Seattle, Washington 98109, USA.

 

6.       Responsible of the project funded  by Ricerca Sanitaria finalizzata Regione  Piemonte- Bando per il finanziamento di Progetti di ricerca sanitaria finalizzata Anno 2008 – BIS:  PREDITTIVITÀ DIAGNOSTICA E PROGNOSTICO-TERAPEUTICA DELLO STATUS GENOMICO NEL  MELANOMA MALIGNO DELLA CUTE, in collaboration with  Prof. Mario Pippione MD, Department of Dermatopathology, University of Turin, Italy and with Prof. ssa Anna Sapino, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italia .

 

7.       Responsible of the project World Wide Style (WWS) 2008-2009 funded  by University of Turin “INNOVATIVE  DIAGNOSTIC APPROACH AND MOLECULAR DEFINITION OF POORLY DIFFERENTIATED THYROID  CARCINOMAS”, in collaboration with  Prof. Ricardo V. Lloyd, Departments Laboratory Medicine  and Pathology, MAYO Clinic, Minnesota - Rochester USA. The PI  has carried out the WWS research at the Mayo Clinic Visiting Clinician Program in 2009.

 

8.       Responsible of the project ex-60% MIUR  funded  by University of Turin (MIUR Università di Torino (ex-60%) anno: 2009-2010.

 

9.       Responsible of the project ex-60% MIUR  funded  by University of Turin (MIUR Università di Torino (ex-60%) anno:  : 2011-2012.

 

·         Co-worker to 3 research projects funded by the Italian Association of Cancer Research (AIRC, 3 projects 2004, 2005, 2007), See website: www.airc.it,

 

a.       Grant Proposal AIRC 2004 GENETIC RELATIONSHIP AMONG ATYPICAL ADENOMATOUS

HYPERPLASIA, BRONCHIOLOALVEOLAR CARCINOMA AND ADENOCARCINOMA OF THE LUNG in collaboration with  Stefania Damiani, Sezione di Anatomia Patologica, Ospedale “M. Malpighi”, Università di Bologna, Ospedale Bellaria, Bologna, Italia.

 

b.       Grant Proposal AIRC 2005: GENETIC AND FUNCTIONAL CHARACTERIZATION OF LOBULAR CARCINOMA OF THE BREAST FOR CLINICAL MANAGEMENT in collaboration with  Prof. Vincenzo  Eusebi MD FRC Path, Sezione di Anatomia Patologica, Ospedale “M. Malpighi”, Università di  Bologna, Ospedale Bellaria, Bologna, Italia.

 

c.        Grant Proposal AIRC 2007: INNOVATIVE DIAGNOSTIC APPROACH AND MOLECULAR DEFINITION OF POORLY DIFFERENTIATED THYROID CARCINOMAS in collaboration with  Prof. Gianni Bussolati MD FRC Path, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italia.

 

 

 

Publications:

Author of 71publications, since 2002, on "peer review journals",4 book chapterS,  and  44 abstracts  published on

peer review jOURNAL

 

The current bibliometric data are

Articles published in journals with impact factor: 71/71;

Impact Factor of the total journal papers: 206,428 

Impact Factor for the average article in a journal:3.88

Number of citations: 1145(Scopus), 912(ISI Web of Science), 1543(Google Scholar) 

h-index: 20(Scopus) 18 (ISI Web of Science), 23(Google Scholar).

 

 

BRIEF TRACK-RECORD OF SOFIA ASIOLI

·         Research of Surgical Pathology at the University of Bologna .

·         Research Collaborator of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

·         Research Collaborator of University of Madison, Wisconsin, USA.

·         Research Colaborator of the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Responsible for the Head and Neck and Neuroendocrine Pathology Group at the Department of Biomedical Science and Human Pathology at Turin University until 31/10/2013

·         Co-responsible for the Head and Neck Pathology Group at the Department of  Department of Biomedical and Neuromotor Sciences at Bologna University from 01/11/2013 to present

·         Member of the Endocrine Pathology Society and of the Head and Neck Italian pathology group (SIAPEC-IAP).

Publications:

Author of 55 publications, since 2002, on "peer review journals", 1 book chapter,  and  41 abstracts  published on

peer review journals.

The current bibliometric data are:  Articles published in journals with impact factor: 60/60; Impact Factor of the total journal papers:192,462Impact Factor for the average article in a journal:3.62Number of citations:746(Scopus), 698 (ISI Web of Science), 1041 (Google Scholar) h-index:16 (Scopus) 15 (ISI Web of Science), 19(Google Scholar).

 

Grant Proposals  (Total =12 grants):

·         Head of research 8 projects funded by the University of Turin (ex-finance 60% MIUR, 5 projects 2008, 2009, 2010, 2011, 2012, 2013) and by Regione Piemonte (Piedmont Healthcare Research aimed Region, 3 projects 2007, 2008, 2008-bis and 1 project of CRT foundation 2008) See Websites: www.sitouniversitario.cineca.it and http://www.ricerca-sanitaria-finalizzata.it.

·         Co-worker to 3 research projects funded by the Italian Association of Cancer Research (AIRC, 3 projects 2004, 2005, 2007), See website: www.airc.it,

·         the PI won the World Wide Style (WWS) project of University of Turin 2009 entitled "innovative and molecular diagnostic approach definition of thyroid poorly differentiated carcinomas," in collaboration with Prof. Ricardo V. Lloyd, Laboratory Medicine and Pathology Departments, MAYO Clinic, Rochester, MN, USA and she has carried out the WWS research at the Mayo Clinic Visiting Clinician Program in 2009.

 

Relevant Research Activities:

·         the PI has identified a new aggressive variant of thyroid carcinoma so called the Hobnail papillary thyroid carcinoma as (see reference 17, Asioli S et al Am J Surg Pathol 2010).

·         the PI showed an extension of the phenotypes associated with mutations in DICER1 including Head and Neck diseases ( see reference Foulkes WD et al. Hum Mutat. 2011) in collaboration with the Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

·         Full knowledge and use of diagnostic morphological techniques (such as fluorescence in situ hybridization and immunohistochemistry) and molecular (comparative genomic hybridization analysis of clonality by analysis of the D-loop region of mitochondrial DNA and the study of micro-RNA, Next Generation Sequensing analysis), in 'field research and diagnostics in surgical pathology and cytopathology.

 

Educational Activity

2005-2013: Assistant Professor of Pathology Anatomy and Histology of University of Turin

2005-2013: Trainer and Tutor for Resident School Of Anatomic Pathology, University of Turin

2005-2013: Assistant Professor of  Cytopathology for Master of II level in cytology, Univeristy of Turin.

2007-2013: Assistant Professor and coordinator  of  Pathology Anatomy and Histology, in School for Cytotechnologists of the University of Cuneo.

2007-2013: Trainer and Tutor for Resident School Of  General Pathology, University of Turin

2007-2013: Assistant Professor of Gastrointestinal pathology  for Master of II level in gastroenterology, Univeristy of Turin.

2007-2013: Assistant Professor of Lung pathology  for Master of II level in thoracic surgery, Univeristy of Turin.

12.12.2013-present: Assistant Professor for Corso di Laurea in Odontoiatria e Protesi Dentaria, university of Bologna.

12.12.2013-present: Trainer and Tutor for Resident School Of Anatomic Pathology, University of Bologna

12.12.2013-present: Trainer and Tutor for Anatomic Pathology, University of Bologna.

 

Awards

Paired Related Homeobox 1 (PRRX1) Is Associated with Epithelial-Mesenchymal Transition (EMT) in Thyroid Tumors . Garcia CM, Guo Z, Hardin H, Buehler D, Nose V, Asioli S,  et al. was selected in the Stowell-Orbison/Surgical Pathology/Autopsy Awards Poster Session at United States & Canadian Academy of Pathology (USCAP) Annual Meeting 2014, San Diego, CA, USA; Modern Pathology 2014 Feb.

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