Foto del docente

Silvia Gobbi

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry

Publications

Elzahhar P.A.; Orioli R.; Hassan N.W.; Gobbi S.; Belluti F.; Labib H.F.; El-Yazbi A.F.; Nassra R.; Belal A.S.F.; Bisi A., Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2024, 266, Article number: 116138 , pp. 1 - 14 [Scientific article]Open Access

Gobbi S.; Martini S.; Rozza R.; Spinello A.; Caciolla J.; Rampa A.; Belluti F.; Zaffaroni N.; Magistrato A.; Bisi A., Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment, «MOLECULES», 2023, 28, Article number: 3047 , pp. 1 - 18 [Scientific article]Open Access

De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena, Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 252, Article number: 115297 , pp. 1 - 15 [Scientific article]Open Access

Seghetti, Francesca; Belluti, Federica; Rampa, Angela; Gobbi, Silvia; Legac, Jenny; Parapini, Silvia; Basilico, Nicoletta; Bisi, Alessandra, Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds, «FUTURE MEDICINAL CHEMISTRY», 2022, 14, pp. 1865 - 1880 [Scientific article]

Seghetti F.; Gobbi S.; Belluti F.; Rampa A.; Bisi A., Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology, «CURRENT MEDICINAL CHEMISTRY», 2022, 29, pp. 4796 - 4830 [Scientific article]Open Access

Rossi, Martina; Cappadone, Concettina; Picone, Giovanna; Bisi, Alessandra; Farruggia, Giovanna; Belluti, Federica; Blasi, Paolo; Gobbi, Silvia; Malucelli, Emil, Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells, «MOLECULES», 2022, 27, Article number: 3751 , pp. 1 - 18 [Scientific article]Open Access

Caciolla J.; Martini S.; Spinello A.; Belluti F.; Bisi A.; Zaffaroni N.; Magistrato A.; Gobbi S., Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2022, 244, Article number: 114802 , pp. 114802 - 114811 [Scientific article]

Bisi A.; Feoli A.; Trezza A.; Viejo L.; Formaggio F.; Bartolini M.; Belluti F.; Gobbi S.; Spiga O.; Caprini M.; de los Rios C.; Castellano S.; Rampa A., Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts, «BIOORGANIC CHEMISTRY», 2022, 129, Article number: 106152 , pp. 106152 - 106166 [Scientific article]

Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A., Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2021, 224, Article number: 113733 , pp. 113733 - 113752 [Scientific article]

Gobbi S.; Belluti F.; Rampa A.; Bisi A., Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century, «MOLECULES», 2021, 26, Article number: 4228 , pp. 4228 - 4241 [Scientific article]Open Access

Bonvicini F.; Belluti F.; Bisi A.; Gobbi S.; Manet I.; Gentilomi G.A., Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm, «RESEARCH IN MICROBIOLOGY», 2021, 172, Article number: 103873 , pp. 1 - 8 [Scientific article]Open Access

Caciolla J.; Picone G.; Farruggia G.; Valenti D.; Rampa A.; Malucelli E.; Belluti F.; Trezza A.; Spiga O.; Iotti S.; Gobbi S.; Cappadone C.; Bisi A., Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer, «BIOORGANIC CHEMISTRY», 2021, 106, Article number: 104460 , pp. 104460 - 104472 [Scientific article]Open Access

Montanari S.; Allara M.; Scalvini L.; Kostrzewa M.; Belluti F.; Gobbi S.; Naldi M.; Rivara S.; Bartolini M.; Ligresti A.; Bisi A.; Rampa A., New Coumarin derivatives as cholinergic and cannabinoid system modulators, «MOLECULES», 2021, 26, Article number: 3254 , pp. 1 - 18 [Scientific article]Open Access

Rampa, Angela; Gobbi, Silvia; Belluti, Federica; Bisi, Alessandra, Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles, «CURRENT MEDICINAL CHEMISTRY», 2021, 28, pp. 2305 - 2327 [Scientific article]Open Access

Seghetti F., Di Martino R.M.C., Catanzaro E., Bisi A., Gobbi S., Rampa A., Canonico B., Montanari M., Krysko D.V., Papa S., Fimognari C., Belluti F., Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery., «MOLECULES», 2020, 25, Article number: 3066 , pp. 1 - 21 [Scientific article]Open Access