Foto del docente

Rita Morigi

Professoressa associata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHEM-07/A Chimica farmaceutica

Pubblicazioni

Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Maccarinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G., Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 166, pp. 514 - 530 [articolo]Open Access

Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico, Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells, in: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium - Abstract Book, 2018, pp. 24 - 24 (atti di: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium, Padova, 26-28 settembre 2018) [atti di convegno-abstract]

Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Locatelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto, Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora, «MEDICINAL CHEMISTRY», 2018, 14, pp. 311 - 319 [articolo]

A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico., R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells., in: AACR Annual Meeting 2018. Chicago, April 14 - 18, 2018. Abstract Book, «CANCER RESEARCH», 2018, 78, pp. 4838 - 4838 (atti di: AACR Annual Meeting 2018., Chicago, USA, April 14 - 18, 2018) [atti di convegno-poster]

R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo, Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents, in: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens. 26th - 28th September 2018 - Padova, Italy - Abstract Book, Padova, 2018, pp. 126 - 126 (atti di: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens., Padova, 26-28 settembre 2018) [atti di convegno-abstract]

Gatti, Rita; Morigi, Rita, 1,4-Anthraquinone: A new useful pre-column reagent for the determination of N-acetylcysteine and captopril in pharmaceuticals by high performance liquid chromatography, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2017, 143, pp. 299 - 304 [articolo]

Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, A Patent Review on Thiazole Derivatives (2008-2013), «ACTA CHIMICA & PHARMACEUTICA INDICA», 2017, 7, Article number: 103, pp. 1 - 35 [articolo]

A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico., G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells., in: 6th International Meeting on Quadruplex Nuceic Acids: G4thering. Prague, May 31st-June 3rd, 2017 - Abstract Book, 2017, pp. 221 - 221 (atti di: 6th International Meeting on Quadruplex Nuceic Acids: G4thering., Praga, Repubblica Ceca, 31 maggio - 03 giugno 2017) [atti di convegno-abstract]

Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective, «BIOENERGETICS», 2017, 6, Article number: Chemistry Journals-17-99R1, pp. 1 - 3 [articolo]

N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziadio, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo., Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives., in: 6th International Meeting on Quadruplex Nuceic Acids: G4thering. Prague, May 31st-June 3rd, 2017 - Abstract Book, 2017, pp. 132 - 132 (atti di: 6th International Meeting on Quadruplex Nuceic Acids: G4thering., Praga, 31 maggio-03 giugno 2017) [atti di convegno-abstract]

Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, 2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014), «EXPERT OPINION ON THERAPEUTIC PATENTS», 2016, 26, pp. 149 - 173 [articolo]

Morigi, Rita; Rambaldi, Mirella; Locatelli, Alessandra; Leoni, Alberto, Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015), «CURRENT MEDICINAL CHEMISTRY», 2016, 23, pp. 3510 - 3527 [articolo]

Graziadio, Alessandra; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella, Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015), «MEDICINAL CHEMISTRY», 2016, 6, pp. 411 - 421 [articolo]

Amato, Jussara; Morigi, Rita; Pagano, Bruno; Pagano, Alessia; Ohnmacht, Stephan; De Magis Alessio; Tiang, Yee-Peng; Capranico, Giovanni; Locatelli, Alessandra; Graziadio, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Novellino, Ettore; Neidle, Stephen; Randazzo, Antonio, Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives, «JOURNAL OF MEDICINAL CHEMISTRY», 2016, 59, pp. 5706 - 5720 [articolo]Open Access

Morigi Rita; Locatelli Alessandra; Leoni Alberto; Mirella Rambaldi, Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity, «RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY», 2015, 10, pp. 280 - 297 [articolo]