From 2009 Jessica Fiori is assistant professor in Medicinal Chemistry at the University of Bologna. Her current research activity is devoted to mass spectrometric strategies for the identification and characterization of bioactive molecules or natural compounds in different matrices and for the study of peptides involved in protein aggregation disorders such as Alzheimer’s disease. Very recently she focused her interest on proteins and peptides involved in pathological events and on gut microbiota metabolites, which provide a relevant contribution to the host’s nutritional, immunological and physiological status. She is author and co-author of many scientific articles published on peer reviewed international journals.
Master Degree in Chemistry and Pharmaceutical
Technology in 1998 from the University of Bologna, PhD in Pharmaceutical Sciences, 2003, from the same University
for studies regarding the photochemical properties of drugs.
After several years of post-doc fellowship, since
December 2008 she works as assistant professor in Medicinal
Chemistry at the Department of Pharmacy and Biotechnology and from 2018 at the Department of Chemistry "G. Ciamician,
University of Bologna. In 2015 she obtained the National Scientific Qualification as Associate Professor in Medicinal Chemistry. In 2018 she obtained the National Scientific Qualification as Associate Professor in Analytical Chemistry. In 2000 she spent a research period at
GlaxoSmithKline (Ware, United Kingdom), carrying out a research
project aimed at the development of analytical methodology for
photostability studies on drugs; in 2005 she collaborated with the
Prof. A. P. Bruins group at the Mass Spectrometry Core Facility,
University of Groningen (The Netherland), working on the
optimization of conditions for effective electrochemical cleavage
of peptides and proteins.
Her work at the Department of Chemistry has been mainly focused on the development of new
analytical methods for the characterization and dosage of drugs and
bioactive molecules. The methodologies involved in these studies
are spectroscopic techniques such as UV and mass spectrometry (MS),
separation techniques, like liquid chromatography (HPLC), gas
chromatography (GC), and combined techniques, i.e. LC-MS, GC-MS,
MALDI-MS (Matrix Assisted Laser Desorption Ionization – MS). The
research interests and applications are: (i) medicinal chemistry
(characterization, determination, dosage of drugs, natural
compounds and bioactive molecules in complex matrices); (ii) proteins, peptides, biomarkers, proteins mutation, acetilation and isoforms,
protein-protein interactions for the study of different pathologies; (iii)
microbiology, interaction between bacteria and human proteins and,
very recently, the determination of gut microbiota metabolites, which provide a relevant
contribution to the host's nutritional, immunological and
physiological status.She has established national and international scientific
collaborations. Dr. Fiori is the author of 68 papers on
international journals, one book chapter, and several oral communications at
From 2018: Professor of Cosmetic ingredient analysis and quality assurance Unit 1-Cosmetic ingredient analysis, Master degree in Advanced Cosmetic Sciences, Università di Bologna, Polo di Rimini.
Dal 2009 al 2016: teaching activity at the corse of Analisi farmaceutica II and Analisi dei Prodotti per la Salute II, 1st cycle degree Controllo di Qualità dei Prodotti per la Salute (CQPS), Scuola di Farmacia e Biotecnologie, Università di Bologna, Polo di Rimini.
International and national research projects, selected for funding based on calls that involved competitive peer-reviewed
2017. Antibiotic prophylaxis in infants with congenital abnormalities of kidney and urinary tract: the impact of the developmental trajectory of gut microbiome assembly, metabolic programming and the gut resistome profile. Progetto finanziato dalla ricerca finalizzata, Ministero della Salute (Project code RF-2016-02363563), WP leader of the Università of Bologna.
2016. Plant food in human evolution: Factors affecting the harvest of nutrients from the floral environment (HARVEST), ERC Starting Grant 2015, Collaborator.
2015-2018. Innovative Food Product Development Cycle: Frame for Stepping Up Research Excellence of FINS – FOODstars. H2020-TWINN-2015 (H2020-EU.4.b. - Twinning of research institutions, project ID: 692276), Collaborator.
2015. Composition of Gut Microbiota and impact on immune system recovery and acute graft versus host disease in pediatric patients undergoing hematopoietic stem cell transplantation”. Finanziato dalla ricerca finalizzata, Ministero della Salute (Project code GR-2013-02357136), Collaborator.
2007-2013. Bio-Inspired Self-assembled Nano-Eanabled Surfaces (BISNES), FP7 SEVENTH FRAMEWORK PROGRAMME THEME 4 NMP - Nanosciences, Nanotechnologies, Materials and new Production Technologies (H2020, Grant No. 214538), Collaborator.
Referee for international scientific journals
Referee for the following international scientific journals: Analytica Chimica Acta, Chromatographia, Journal of Chromatography A, Journal of Chromatography B, Journal of Pharmaceutical and Biomedical Analysis, Analytical Letters.