Foto del docente

Giuseppina Di Stefano

Associate Professor

Department of Medical and Surgical Sciences

Academic discipline: MED/04 Experimental Medicine and Pathophysiology

Publications

Di Stefano G; Fiume L; Domenicali M; Busi C; Chieco P; Kratz F; Lanza M; Mattioli A; Pariali M; Bernardi M., Doxorubicin coupled to lactosaminated albumin: effects on rats with liver fibrosis and cirrhosis., «DIGESTIVE AND LIVER DISEASE», 2006, 38, pp. 404 - 408 [Scientific article]

Di Stefano G.; Busi C.; Chieco P.; Pariali M.; Fiume L., Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas., «DIGESTIVE AND LIVER DISEASE», 2006, 38, pp. 284 - 285 [Scientific article]

Patent n. PCT/EP2006/066489, Use of conjugates of doxorubicin with lactosaminated albumin..

FIUME L.; BOLONDI L.; BUSI C.; CHIECO P.; KRATZ F.; LANZA M.; MATTIOLI A.; DI STEFANO G., Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine., «JOURNAL OF HEPATOLOGY», 2005, 43, pp. 645 - 652 [Scientific article]

DI STEFANO G.; FIUME L.; BOLONDI L.; LANZA M.; PARIALI M.; CHIECO P., Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors., «LIVER INTERNATIONAL», 2005, 25, pp. 854 - 860 [Scientific article]

Patent n. PCT/IT2005/000257, Process for the preparation of doxorubicin conjugates with lactosaminated human albumin.

Patent n. MI2005A001743, Uso di coniugati della doxorubicina con albumina lattosaminata.

DI STEFANO G.; LANZA M.; KRATZ F.; MERINA L.; FIUME L., A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate., «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2004, 23, pp. 393 - 397 [Scientific article]

DI STEFANO G.; DERENZINI M.; KRATZ F.; LANZA M.; FIUME L., Liver targeted doxorubicin: effects on rat regenerating hepatocytes., «LIVER INTERNATIONAL», 2004, 24, pp. 246 - 252 [Scientific article]

Patent n. MI2004A000928, Procedura per la preparazione di coniugati della doxorubicina con l’albumina umana lattosaminata.

Dall'Olio, F; Malagolini, N; Di Stefano, G; Ciambella, M; Serafini, F, Postnatal development of rat colon epithelial cells is associated with changes in the expression of the beta 1,4-N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen of alpha 2,6-sialyltransferase activity towards N-acetyl-lactosamine, «BIOCHEMICAL JOURNAL», 1990, 270, pp. 519 - 524 [Scientific article]

Malagolini, N; Dall'Olio, F; Di Stefano, G; Minni, F; Marrano, D; Serafini, F, Expression of UDP-GalNAc:NeuAc alpha 2,3Gal beta-R beta 1,4(GalNAc to Gal) N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen in human large intestine and colorectal carcinomas, «CANCER RESEARCH», 1989, 49, pp. 6466 - 6470 [Scientific article]

Dall'Olio, F; Malagolini, N; di Stefano, G; Minni, F; Marrano, D; Serafini, F, Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues, «INTERNATIONAL JOURNAL OF CANCER», 1989, 44, pp. 434 - 439 [Scientific article]

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