Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea, The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2022, 23, Article number: 8338 , pp. 1 - 14 [Scientific article]Open Access
Balboni, A.; Govoni, M.; Rossi, V.; Roberti, M.; Cavalli, A.; Di Stefano, G.; Manerba, M., Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2021, 1865, Article number: 129760 , pp. 1 - 10 [Scientific article]Open Access
Govoni M.; Rossi V.; Di Stefano G.; Manerba M., Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin, «PATHOLOGY ONCOLOGY RESEARCH», 2021, 27, Article number: 1609951 , pp. 1 - 9 [Scientific article]Open Access
Bagnolini G.; Milano D.; Manerba M.; Schipani F.; Ortega J.A.; Gioia D.; Falchi F.; Balboni A.; Farabegoli F.; De Franco F.; Robertson J.; Pellicciari R.; Pallavicini I.; Peri S.; Minucci S.; Girotto S.; Di Stefano G.; Roberti M.; Cavalli A., Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 2588 - 2619 [Scientific article]Open Access
Bagnolini, Greta; Balboni, Andrea; Manerba, Marcella; Farabegoli, Fulvia; DI STEFANO, Giuseppina; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy, in: 1, 2019(atti di: WORKSHOP: I chimici per le biotecnologie, Milan, 22 February 2019) [Poster]
Bagnolini, G.; Balboni, A.; Manerba, M.; Di Stefano, G.; Roberti, M.; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and synergize with Olaparib as new anticancer drug discovery concept, in: 1, 2019, pp. 1 - 1 (atti di: XXVI National Meeting in Medicinal Chemistry, Milan, 16-19 July 2019) [Contribution to conference proceedings]
Manerba, Marcella; Govoni, Marzia; Manet, Ilse; Leale, Antoniofrancesco; Comparone, Antonietta; Di Stefano, Giuseppina, Metabolic activation triggered by cAMP in MCF-7 cells generates lethal vulnerability to combined oxamate/etomoxir, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2019, 1863, pp. 1177 - 1186 [Scientific article]
Roberti, Marinella; Schipani, Fabrizio; Bagnolini, Greta; Milano, Domenico; Giacomini, Elisa; Falchi, Federico; Balboni, Andrea; Manerba, Marcella; Farabegoli, Fulvia; Francesca De Franco, ; Robertson, Janet; Minucci, Saverio; Pallavicini, Isabella; DI STEFANO, Giuseppina; Girotto, Stefania; Pellicciari, Roberto; and Andrea Cavalli, ; Cavalli, Andrea, Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with
Olaparib in Pancreatic Cancer Cells, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 165, pp. 80 - 92 [Scientific article]
Bagnolini, Greta; Balboni, Andrea; Farabegoli, Fulvia; DI STEFANO, Giuseppina; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in cancer treatment, in: 1, 2018, pp. 1 - 1 (atti di: XVIII Giornata della Chimica dell’Emilia Romagna, Parma, December 2018) [Contribution to conference proceedings]
Manerba M, Di Ianni L, Govoni M, Comparone A, Di Stefano G., The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells, «PLOS ONE», 2018, 13, Article number: e0202588 , pp. 1 - 17 [Scientific article]Open Access
Bagnolini, Greta; Falchi, F.; Farabegoli, F.; Di Stefano, G.; Roberti, M.; Cavalli, A., Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy, in: 1, 2017, pp. 1 - 1 (atti di: XVII Giornata della chimica dell'Emilia-Romagna 2024, Bologna, December 2017) [Contribution to conference proceedings]
Manerba, Marcella; Di Ianni, Lorenza; Govoni, Marzia; Roberti, Marinella; Recanatini, Maurizio; Di Stefano, Giuseppina, Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells, «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2017, 96, pp. 37 - 44 [Scientific article]Open Access
Manerba, Marcella; Di Ianni, Lorenza; Govoni, Marzia; Roberti, Marinella; Recanatini, Maurizio; Di Stefano, Giuseppina, LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells, «EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES», 2017, 105, pp. 91 - 98 [Scientific article]Open Access
Falchi, Federico; Giacomini, Elisa; Masini, Tiziana; Boutard, Nicolas; Di Ianni, Lorenza; Manerba, Marcella; Farabegoli, Fulvia; Rossini, Lara; Robertson, Janet; Minucci, Saverio; Pallavicini, Isabella; Di Stefano, Giuseppina; Roberti, Marinella; Pellicciari, Roberto; Cavalli, Andrea, Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors, «ACS CHEMICAL BIOLOGY», 2017, 12, pp. 2491 - 2497 [Scientific article]
DI STEFANO, Giuseppina; Manerba, Marcella; DI IANNI, Lorenza; Fiume, Luigi, Lactate dehydrogenase inhibition: Exploring possible applications beyond cancer treatment, «FUTURE MEDICINAL CHEMISTRY», 2016, 8, pp. 713 - 725 [Scientific article]
