Foto del docente

Giovanni Perini

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/18 Genetics

Director of First Cycle Degree in Biotechnology

Teaching

Recent dissertations supervised by the teacher.

First cycle degree programmes dissertations

  • A Research Proposal: Dissecting the molecular interactions between MYCN and SF3B2 in MYCN-amplified neuroblastoma and how they impact on mRNA splicing
  • Caratterizzazione dell’interazione tra due corepressori trascrizionali coinvolti nell’oncogenesi del neuroblastoma
  • Investigation of conditional expression and binding of nanobody-dCas9-FH to GFP-egg protein in Drosophila melanogaster germline cells and early embryo
  • Investigation of PCGF2/4 function in human cortical organoids using CRISPR/Cas9
  • Research proposal : dissecting MYC(N) and MLL interaction in MYC amplified tumors.
  • Studio degli effetti benefici delle cellule precursori neurali in un modello sperimentale della sindrome di Rett
  • Studio del ruolo di MYCN nella regolazione dell’interazione tra E2F3A e KAT2A in neuroblastoma

Second cycle degree programmes dissertations

  • Biochemical dissection of the PP2A complex
  • MYCN come induttore dell'interazione tra E2F3a e KAT2A in Neuroblastoma
  • Studio dei domini NERVY HOMOLOGY REGIONS del co-repressore RUNX1T1 in neuroblastoma
  • Studio di un nuovo complesso di regolazione trascrizionale CoREST-like in neuroblastoma

PhD programmes thesis

  • Multi-omic analyses of the MYCN network unveil new potential vulnerabilities in childhood neuroblastoma