Foto del docente

Giovanni Perini

Professore ordinario

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: BIO/18 GENETICA

Didattica

Ultime tesi seguite dal docente

Tesi di Laurea

  • A polygenic score to assess pancreatic cancer risk
  • Applicazione della tecnica di Proximity Ligation Assay (PLA) per verificare interazioni proteina-proteina in cellule di Neuroblastoma
  • Characterization of a library of genes with unknown or poorly defined function in Escherichia coli through optogenetics
  • Investigating the role of C/EBPa as an orchestrator of Nanog expression, through chromatin topology alternation
  • MEA and LMT An all-encompassing standardized drug screening protocol for Fragile X Syndrome
  • Molecular validation of genes involved in the formation of the endocardium in mammalian heart development
  • Role of genetic polymorphisms in prognosis of multiple myeloma
  • Studio dell'asse E2F3 - KAT2A in neuroblastoma
  • Targeted bisulfite sequencing for the analysis of DNA methylation profiles of repetitive elements of the human genome

Tesi di Laurea Magistrale

  • Engineering of an Orthogonal anti-GD2 Phage Vector Platform for Photodynamic Therapy of Neuroblastoma
  • Enhance the efficacy of calicheamicin-conjugate therapeutic antibody through PARP1 inhibition against acute lymphoblastic leukemia cells
  • miR-1290 and miR-320c: Potential Circulating Biomarkers for Neuroendocrine Carcinomas
  • Modulazione del signalling inositide-dipendente in modelli cellulari leucemici
  • MYCN overcomes RB1 function in high-risk Neuroblastoma

Tesi di Dottorato

  • EBV Type II latency relies on PARP1 activity and is essential for gastric epithelial cell transformation in EBV-associated Gastric Cancer (EBVaGC)
  • Harnessing the cellular and molecular complexity of high-risk neuroblastoma to investigate novel potential treatment approaches
  • Role of CARM1 (PRMT4) in high grade serous ovarian cancer metabolism and function of PRMT5 in ARID1A- deficient endometrial cancer invasion