Dissertation topics suggested by the teacher.
Research line 1: Novel molecular strategies for cardiac regeneration
Heart dysfunction as a consequence of severe damages, such those induced by myocardial infarction, is a crucial public health problem and a leading cause of death in the western world today.
The aim of the studies carried out by our research group is to identify novel strategies for heart regeneration following severe damages, by direct stimulation of cell dedifferentiation, cell cycle re-entry and proliferation of endogenous cardiac muscle cells (cardiomyocytes).
This project involves the evaluation of differentiation status and proliferation of cardiomyocytes following the administration of specific stimuli (hormones, cytokines, growth factors...) or gene manipulation, and the analysis of the downstream molecular mechanisms.
Recent dissertations supervised by the teacher.
Second cycle degree programmes dissertations
- The impact of selective glucocorticoid receptor modulation on cardiomyocyte proliferation
- The role of ERBB2 in cellular senescence of breast epithelial cells: implications for cancer dormancy
- The role of Mineralocorticoid Receptor signaling in cardiac cell proliferation.
